Autoimmune Diseases
|
|
0.900 |
GeneticVariation
|
BEFREE |
STAT4 polymorphism, rs7574865 is linked to various autoimmune diseases such as systemic lupus erythematosus and rheumatoid arthritis.
|
27960128 |
2017 |
Autoimmune Diseases
|
|
0.900 |
GeneticVariation
|
BEFREE |
Here we demonstrate for the first time, in a genetically homogeneous population, the association of the STAT4 rs7574865 G/T polymorphism, which has been shown to be associated with these autoimmune diseases, with susceptibility to type 1 diabetes (T1D).
|
18703106 |
2008 |
Autoimmune Diseases
|
|
0.900 |
GeneticVariation
|
BEFREE |
The T allele of rs7574865 in STAT4 confers risk of developing autoimmune disorders.
|
26569609 |
2015 |
Autoimmune Diseases
|
|
0.900 |
GeneticVariation
|
BEFREE |
Taking into consideration that the different autoimmune diseases may share some common pathogenetic pathways, the aim of the present study was to evaluate the role of STAT4 rs7574865 polymorphism on acute allograft rejection.
|
21237270 |
2011 |
Autoimmune Diseases
|
|
0.900 |
GeneticVariation
|
GWASDB |
Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci.
|
21383967 |
2011 |
Autoimmune Diseases
|
|
0.900 |
GeneticVariation
|
BEFREE |
We found that mutated allele T of the STAT4 rs7574865 SNP, which previously was implicated in the predisposition to many autoimmune diseases, were more common in individuals with psoriasis than in controls (p = 0.045, odds ratio = 1.42, 95% confidence interval 1.01-2.00), thus concluding that the polymorphism examined is associated with the development of psoriasis in our population.
|
19500629 |
2009 |
Autoimmune Diseases
|
|
0.900 |
GeneticVariation
|
BEFREE |
Our data strengthen STAT4 rs7574865 polymorphism as a susceptibility factor for RA and SLE and provide further evidence for a common origin of autoimmune diseases.
|
18432273 |
2008 |
Autoimmune Diseases
|
|
0.900 |
GeneticVariation
|
BEFREE |
Recent studies have indicated associations of rs7574865 single nucleotide polymorphism (SNP) in the STAT4 gene with various autoimmune diseases.
|
27126090 |
2017 |
Autoimmune Diseases
|
|
0.900 |
GeneticVariation
|
BEFREE |
We recently reported for the first time as a PS-associated SNP the signal transducer and activator of transcription-4 (STAT4) rs7574865 polymorphism, which is also associated with several autoimmune diseases.
|
20039785 |
2010 |
Autoimmune Diseases
|
|
0.900 |
GeneticVariation
|
BEFREE |
But, no significant differences in allele and genotype frequencies of STAT4 rs7574865 polymorphism were detected according to the presence of another autoimmune disease, nodules and in HLA-DRB1*04 and HLA-DRB1*0404 positive subgroups.
|
21418779 |
2011 |
Autoimmune Diseases
|
|
0.900 |
GeneticVariation
|
GWASCAT |
Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci.
|
21383967 |
2011 |
Autoimmune Diseases
|
|
0.900 |
GeneticVariation
|
BEFREE |
This meta-analysis demonstrates that the STAT4 rs7574865 T allele confers susceptibility to SLE, RA, T1D, SSc, JIA, APS, IBD-UC, and pSS patients, supporting the hypothesis of association between STAT4 gene polymorphism and subgroup of autoimmune diseases.
|
22714917 |
2012 |