rs759834365, BDNF-AS;BDNF

N. diseases: 237
Disease: Amyloidosis ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Amyloidosis
CUI: C0002726
Disease: Amyloidosis
0.050 GeneticVariation BEFREE While allelic variation in BDNF Val66Met may influence Aβ+ related neurodegeneration and memory loss over the short term, this is not related to serum mBDNF. 28720165 2017
Amyloidosis
CUI: C0002726
Disease: Amyloidosis
0.050 GeneticVariation BEFREE To examine the influence of the brain-derived neurotrophic factor (<i>BDNF</i>) Val66Met polymorphism on longitudinal cognitive trajectories in a large, cognitively healthy cohort enriched for Alzheimer disease (AD) risk and to understand whether β-amyloid (Aβ) burden plays a moderating role in this relationship. 28468845 2017
Amyloidosis
CUI: C0002726
Disease: Amyloidosis
0.050 GeneticVariation BEFREE Among Aβ+ women, ε4 carriers reported greater anxiety symptoms than non-ε4 carriers (d = 0.83), and female BDNF rs6265 Val66 Met allele carriers reported greater depressive symptoms (d = 0.29). 27742526 2016
Amyloidosis
CUI: C0002726
Disease: Amyloidosis
0.050 GeneticVariation BEFREE We aimed to determine the effect of BDNF Val66Met on cognitive function, hippocampal function, tau and amyloid-β in preclinical autosomal dominant Alzheimer's disease. 27521573 2016
Amyloidosis
CUI: C0002726
Disease: Amyloidosis
0.050 GeneticVariation BEFREE BDNF Val66Met did not relate to the amount of Aβ or to the rate of Aβ accumulation in either group. 23769397 2013