Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Borderline Personality Disorder
CUI: C0006012
Disease: Borderline Personality Disorder
0.090 GeneticVariation BEFREE Amygdala responses across genotypes (Val66Met SNP Met allele-carriers vs. Non-Met carriers) and diagnoses (HC, BPD, SPD) were examined with ANOVA. 28371657 2017
Borderline Personality Disorder
CUI: C0006012
Disease: Borderline Personality Disorder
0.090 GeneticVariation BEFREE The positive association of BNDF Val66Met with high BMI values replicates previous findings in patients with SCZ and indicates the BDNF Val66Met genotype as a potential risk factor for obesity and insulin resistance measures in patients with BPD receiving antipsychotics as well. 25874530 2015
Borderline Personality Disorder
CUI: C0006012
Disease: Borderline Personality Disorder
0.090 GeneticVariation BEFREE Overall, there was no significant difference in allelic distribution of Val66Met polymorphism between patients and controls with a pooled OR = 1.03 (95% CI 0.98, 1.08) although there was a trend towards association between Val66Met polymorphism and BPD in Caucasians with an OR of 1.08 (95% CI 1.00, 1.16). 25539739 2014
Borderline Personality Disorder
CUI: C0006012
Disease: Borderline Personality Disorder
0.090 GeneticVariation BEFREE The association between Val66Met polymorphism and BPD, treatment response to mood stabilizers, was estimated. 22548711 2012
Borderline Personality Disorder
CUI: C0006012
Disease: Borderline Personality Disorder
0.090 GeneticVariation BEFREE The interrelations between serious life events, impulsive aggression and the BDNF Val(66)Met polymorphism as well as their implication for BPD are far from understood and require further investigations. 19817874 2010
Borderline Personality Disorder
CUI: C0006012
Disease: Borderline Personality Disorder
0.090 GeneticVariation BEFREE Previous studies have suggested that the Val66Met (also known as rs6265 or G196A) variant of BDNF is associated with bipolar disorder (BPD), but the results have been inconclusive. 19330778 2010
Borderline Personality Disorder
CUI: C0006012
Disease: Borderline Personality Disorder
0.090 GeneticVariation BEFREE The study demonstrates that the BDNF C-270T and Val66Met polymorphisms are unlikely to contribute to the genetic predisposition to BPD as a whole. 18242852 2008
Borderline Personality Disorder
CUI: C0006012
Disease: Borderline Personality Disorder
0.090 GeneticVariation BEFREE Two family-based association studies showed that the Val allele of the functional polymorphism Val66Met in the BDNF gene is associated with BPD; however, others could not confirm the results. 16152572 2005
Borderline Personality Disorder
CUI: C0006012
Disease: Borderline Personality Disorder
0.090 GeneticVariation BEFREE There was no evidence for an allelic or genotypic association of two polymorphisms (-1360C>T and 196G>A) of the BDNF gene with BPD. 12524161 2003