Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Presenile dementia
CUI: C0011265
Disease: Presenile dementia
0.060 GeneticVariation BEFREE A total of 1,081 adults without dementia (375 healthy subjects and 706 individuals with mild cognitive impairment) were recruited from the Alzheimer's Disease Neuroimaging Initiative (ADNI) to test the influence of BDNF Val66Met polymorphism on cognitive impairment, brain structure atrophy, and change in the levels of CSF biomarkers. 30775992 2019
Presenile dementia
CUI: C0011265
Disease: Presenile dementia
0.060 GeneticVariation BEFREE Neither allelic nor genotypic BDNF Val66Met SNP was associated with dementia or with BP (associated or not with clinical manifestation of dementia). 30220011 2018
Presenile dementia
CUI: C0011265
Disease: Presenile dementia
0.060 GeneticVariation BEFREE Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism and post-stroke dementia: a hospital-based study from northern Iran. 27071687 2016
Presenile dementia
CUI: C0011265
Disease: Presenile dementia
0.060 GeneticVariation BEFREE Effect of BDNF Val66Met polymorphism on regional white matter hyperintensities and cognitive function in elderly males without dementia. 24275008 2014
Presenile dementia
CUI: C0011265
Disease: Presenile dementia
0.060 GeneticVariation BEFREE Among 200 outpatients with dementia and MCI, 146 outpatients with mild AD or A-MCI were recruited and divided into two genotypic groups, valine homozygosity (Val/Val) and methionine (Met) carriers, based on the representative BDNF functional polymorphism Val66Met. 22699449 2012
Presenile dementia
CUI: C0011265
Disease: Presenile dementia
0.060 GeneticVariation BEFREE Role of BDNF val66met polymorphism on the association between physical activity and incident dementia. 20172629 2011