Disease Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Psychotic Disorders
CUI: C0033975
Disease: Psychotic Disorders
0.100 GeneticVariation BEFREE Although an interaction between COMT Val158Met and BDNF Val66Met polymorphisms with cannabis use has been proposed with respect to the risk of psychosis emergence, findings remain inconclusive. 28142064 2017
Psychotic Disorders
CUI: C0033975
Disease: Psychotic Disorders
0.100 GeneticVariation BEFREE Here we comprehensively review the role and relevance of the Val66Met polymorphism in psychiatric disorders, with emphasis on suicidal behavior and anxiety, eating, mood and psychotic disorders. 25824305 2016
Psychotic Disorders
CUI: C0033975
Disease: Psychotic Disorders
0.100 GeneticVariation BEFREE Further, our study supports a two hit model including a history of childhood trauma as well as genetic vulnerability (met carriers of the BDNF val66met) behind reduced volume of hippocampal subfields in psychosis. 25246365 2015
Psychotic Disorders
CUI: C0033975
Disease: Psychotic Disorders
0.100 GeneticVariation BEFREE BDNF val66met modulates the association between childhood trauma, cognitive and brain abnormalities in psychoses. 23876786 2014
Psychotic Disorders
CUI: C0033975
Disease: Psychotic Disorders
0.100 GeneticVariation BEFREE The present study aimed to explore possible effects of BDNF Val66Met polymorphism variations on progressive structural brain changes after 3 years from the first episode of psychosis. 23748016 2014
Psychotic Disorders
CUI: C0033975
Disease: Psychotic Disorders
0.100 GeneticVariation BEFREE BDNF Val66Met and spontaneous dyskinesias in non-clinical psychosis. 22766130 2013
Psychotic Disorders
CUI: C0033975
Disease: Psychotic Disorders
0.100 GeneticVariation BEFREE Hippocampal volume and the brain-derived neurotrophic factor Val66Met polymorphism in first episode psychosis. 22192502 2012
Psychotic Disorders
CUI: C0033975
Disease: Psychotic Disorders
0.100 GeneticVariation BEFREE The Met allele of the functional polymorphism, BDNF Val66Met, is associated with psychotic disorders. 21728904 2012
Psychotic Disorders
CUI: C0033975
Disease: Psychotic Disorders
0.100 GeneticVariation BEFREE The results had adequate statistical power to suggest that BDNF Val66Met was not related to susceptibility to AD or the onset of AD, but that presence of one or two Met alleles of BDNF Val66Met polymorphism might present a risk factor for psychosis in AD. 21044653 2011
Psychotic Disorders
CUI: C0033975
Disease: Psychotic Disorders
0.100 GeneticVariation BEFREE We performed a family-based association study and ETDT analyses of the Val66Met polymorphism in nuclear families with at least one subject affected by major psychosis with suicidal behaviour, and compared allele-specific mRNA levels in post-mortem brain samples from suicide and non-suicide victims. 20726824 2011
Psychotic Disorders
CUI: C0033975
Disease: Psychotic Disorders
0.100 GeneticVariation BEFREE Our findings suggest that the BDNF Val66Met polymorphism may contribute to methamphetamine dependence and psychosis in the Chinese population but not in other Malaysian ethnicities. 20736000 2011
Psychotic Disorders
CUI: C0033975
Disease: Psychotic Disorders
0.100 GeneticVariation BEFREE The Val66Met polymorphism of the brain-derived neurotrophic factor gene is associated with risk for psychosis: evidence from a family-based association study. 16389585 2006