|
Multiple endocrine neoplasia Type 2
|
|
0.730 |
CausalMutation
|
CLINVAR |
Different RET gene mutation-induced multiple endocrine neoplasia type 2A in 3 Chinese families.
|
28099363 |
2017 |
|
Multiple endocrine neoplasia Type 2
|
|
0.730 |
GeneticVariation
|
BEFREE |
The present study identified the clinical features of the largest multiple endocrine neoplasia type 2 (MEN2) A pedigree from China, with a novel double missense <i>rearranged during transfection (RET)</i> mutation (C634Y/D707E).
|
28943896 |
2017 |
|
Multiple endocrine neoplasia Type 2
|
|
0.730 |
CausalMutation
|
CLINVAR |
Prophylactic thyroidectomy for asymptomatic 3-year-old boy with positive multiple endocrine neoplasia type 2A mutation (codon 634).
|
24684035 |
2015 |
|
Multiple endocrine neoplasia Type 2
|
|
0.730 |
CausalMutation
|
CLINVAR |
High Discrepancy of Driver Mutations in Patients with NSCLC and Synchronous Multiple Lung Ground-Glass Nodules.
|
25629635 |
2015 |
|
Multiple endocrine neoplasia Type 2
|
|
0.730 |
CausalMutation
|
CLINVAR |
Molecular diagnosis and comprehensive treatment of multiple endocrine neoplasia type 2 in Southeastern Chinese.
|
25628771 |
2015 |
|
Multiple endocrine neoplasia Type 2
|
|
0.730 |
CausalMutation
|
CLINVAR |
Twenty years of lesson learning: how does the RET genetic screening test impact the clinical management of medullary thyroid cancer?
|
25440022 |
2015 |
|
Multiple endocrine neoplasia Type 2
|
|
0.730 |
CausalMutation
|
CLINVAR |
RET mutations in a large indian family with medullary thyroid carcinoma.
|
25143909 |
2014 |
|
Multiple endocrine neoplasia Type 2
|
|
0.730 |
CausalMutation
|
CLINVAR |
Characterization of wild-type and mutated RET proto- oncogene associated with familial medullary thyroid cancer.
|
24716929 |
2014 |
|
Multiple endocrine neoplasia Type 2
|
|
0.730 |
CausalMutation
|
CLINVAR |
Comprehensive analysis of RET gene should be performed in patients with multiple endocrine neoplasia type 2 (MEN 2) syndrome and no apparent genotype-phenotype correlation: an appraisal of p.Y791F and p.C634Y RET mutations in five unrelated Brazilian families.
|
23723040 |
2013 |
|
Multiple endocrine neoplasia Type 2
|
|
0.730 |
GeneticVariation
|
BEFREE |
Comprehensive analysis of RET gene should be performed in patients with multiple endocrine neoplasia type 2 (MEN 2) syndrome and no apparent genotype-phenotype correlation: an appraisal of p.Y791F and p.C634Y RET mutations in five unrelated Brazilian families.
|
23723040 |
2013 |
|
Multiple endocrine neoplasia Type 2
|
|
0.730 |
CausalMutation
|
CLINVAR |
Predominant RET Germline Mutations in Exons 10, 11, and 16 in Iranian Patients with Hereditary Medullary Thyroid Carcinoma.
|
21765987 |
2011 |
|
Multiple endocrine neoplasia Type 2
|
|
0.730 |
CausalMutation
|
CLINVAR |
Predominant RET Germline Mutations in Exons 10, 11, and 16 in Iranian Patients with Hereditary Medullary Thyroid Carcinoma.
|
21765987 |
2011 |
|
Multiple endocrine neoplasia Type 2
|
|
0.730 |
CausalMutation
|
CLINVAR |
Coincidence of multiple endocrine neoplasia type 2A with acromegaly.
|
20739875 |
2010 |
|
Multiple endocrine neoplasia Type 2
|
|
0.730 |
GeneticVariation
|
BEFREE |
Three different known RET germline mutations in exon 11 (codon 634), p.Cys634Arg (c1900 T-->C) (de novo case), p.Cys634Phe (c1901 G-->T), p.Cys634Trp (c1902 C-->G), were detected in three individuals with MEN2 phenotype.
|
19841562 |
2010 |
|
Multiple endocrine neoplasia Type 2
|
|
0.730 |
CausalMutation
|
CLINVAR |
Medullary thyroid carcinoma identified within the first year of life in children with hereditary multiple endocrine neoplasia type 2A (codon 634) and 2B.
|
19240193 |
2009 |
|
Multiple endocrine neoplasia Type 2
|
|
0.730 |
CausalMutation
|
CLINVAR |
Familial prevalence and age of RET germline mutations: implications for screening.
|
18062802 |
2008 |
|
Multiple endocrine neoplasia Type 2
|
|
0.730 |
CausalMutation
|
CLINVAR |
RET genetic screening in patients with medullary thyroid cancer and their relatives: experience with 807 individuals at one center.
|
17895320 |
2007 |
|
Multiple endocrine neoplasia Type 2
|
|
0.730 |
CausalMutation
|
CLINVAR |
Pheochromocytoma penetrance varies by RET mutation in MEN 2A.
|
18063059 |
2007 |
|
Multiple endocrine neoplasia Type 2
|
|
0.730 |
CausalMutation
|
CLINVAR |
Genotype-phenotype correlations in Hungarian patients with hereditary medullary thyroid cancer.
|
16865647 |
2006 |
|
Multiple endocrine neoplasia Type 2
|
|
0.730 |
CausalMutation
|
CLINVAR |
Occurrence of the Cys611Tyr mutation and a novel Arg886Trp substitution in the RET proto-oncogene in multiple endocrine neoplasia type 2 families and sporadic medullary thyroid carcinoma cases originating from the central region of Portugal.
|
16712668 |
2006 |
|
Multiple endocrine neoplasia Type 2
|
|
0.730 |
CausalMutation
|
CLINVAR |
Clinical and biochemical features of sporadic and hereditary phaeochromocytomas: an analysis of 41 cases investigated in a single endocrine centre.
|
15452453 |
2004 |
|
Multiple endocrine neoplasia Type 2
|
|
0.730 |
CausalMutation
|
CLINVAR |
The oncogenic activity of RET point mutants for follicular thyroid cells may account for the occurrence of papillary thyroid carcinoma in patients affected by familial medullary thyroid carcinoma.
|
15277225 |
2004 |
|
Multiple endocrine neoplasia Type 2
|
|
0.730 |
CausalMutation
|
CLINVAR |
RET oncogene mutations in medullary thyroid carcinoma in Mexican families.
|
12604374 |
2004 |
|
Multiple endocrine neoplasia Type 2
|
|
0.730 |
CausalMutation
|
CLINVAR |
RET oncogene mutations in medullary thyroid carcinoma in Mexican families.
|
12604374 |
2004 |
|
Multiple endocrine neoplasia Type 2
|
|
0.730 |
CausalMutation
|
CLINVAR |
Acceptable age for prophylactic surgery in children with multiple endocrine neoplasia type 2a.
|
12711285 |
2003 |