rs765670175, PSEN1

N. diseases: 7
Disease: Presenile dementia ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Presenile dementia
CUI: C0011265
Disease: Presenile dementia
0.020 GeneticVariation BEFREE We herein report the case of a German EOAD patient with a family history of dementia and a missense mutation at codon 141 (N141I) </span>of the PSEN2 gene. 19073399 2008
Presenile dementia
CUI: C0011265
Disease: Presenile dementia
0.020 GeneticVariation BEFREE The study provides support for the potential pharmacogenomic identification of N141I PS2 FAD cases that might preferentially benefit from inhibition of COX-2 during the progression of clinical dementia. 16331303 2006