rs77375493, INSL6;JAK2

N. diseases: 187
Disease: Activated Protein C Resistance ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Activated Protein C Resistance
CUI: C0600433
Disease: Activated Protein C Resistance
0.010 GeneticVariation BEFREE These results support a role for platelet turnover, factor V, and aAPCR in the thrombosis of ET as well as the association between JAK2 V617F allele burden and either decreased free PS or increased TF and soluble markers of platelet and endothelial activation. 19105233 2009