Disease Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Diabetes Mellitus, Non-Insulin-Dependent
0.860 GeneticVariation BEFREE Although the influence of a common variant in the glucokinase regulatory gene (GCKR rs780094) in type 2 diabetes mellitus has been well documented, less data however, is available of its role in gestational diabetes mellitus (GDM). 29410004 2018
Diabetes Mellitus, Non-Insulin-Dependent
0.860 GeneticVariation GWASCAT Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease. 28869590 2017
Diabetes Mellitus, Non-Insulin-Dependent
0.860 GeneticVariation BEFREE Although studies have suggested that rs780094, a common variant in the glucokinase regulatory (GCKR) gene to be associated with type 2 diabetes, obesity, and their related traits, the genetic basis of the association between GCKR rs780094 and nonalcoholic fatty liver disease (NAFLD) is still being examined. 25167786 2015
Diabetes Mellitus, Non-Insulin-Dependent
0.860 GeneticVariation BEFREE Our meta-analyses demonstrated that GCKR rs780094 variant confers high cross-ethnicity risk for the development of T2DM, while significant associations between GCK, MTNR1B and G6PC2 variants and T2DM risk are limited to Caucasians. 23840762 2014
Diabetes Mellitus, Non-Insulin-Dependent
0.860 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. 22325160 2012
Diabetes Mellitus, Non-Insulin-Dependent
0.860 GeneticVariation GWASCAT Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. 22885922 2012
Diabetes Mellitus, Non-Insulin-Dependent
0.860 GeneticVariation BEFREE Recently, the association of the natural variants rs1260326 and rs780094 of the glucokinase regulatory protein (GCKR) gene with increased fasting triglycerides and decreased fasting plasma glucose in diabetic adults was reported; the minor alleles were also found to reduce the risk of type 2 diabetes. 21511510 2012
Diabetes Mellitus, Non-Insulin-Dependent
0.860 GeneticVariation BEFREE Consistent with observations in white Europeans, the GCKR rs780094 polymorphism contributes to the risk of type 2 diabetes and dyslipidaemia in Han Chinese individuals. 19241058 2009
Diabetes Mellitus, Non-Insulin-Dependent
0.860 GeneticVariation BEFREE The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes. 18008060 2008
Diabetes Mellitus, Non-Insulin-Dependent
0.860 GeneticVariation GWASDB Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. 17463246 2007