DisGeNET - a database of gene-disease associations

rs780094, GCKR

N. diseases: 62

Disease: Gestational Diabetes ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Gestational Diabetes

CUI:	C0085207
Disease:	Gestational Diabetes

0.040

GeneticVariation

BEFREE

GCKR rs780094 and CDKN2A/B rs10811661 polymorphisms were moderately associated with GDM risk.

30074065

2018

Gestational Diabetes

CUI:	C0085207
Disease:	Gestational Diabetes

0.040

GeneticVariation

BEFREE

The GCKR rs780094, SLC30A8 rs13266634 and FTO rs9939609 SNPs were demonstrated to be the potential biomarkers for GDM risk prediction.

30091126

2018

Gestational Diabetes

CUI:	C0085207
Disease:	Gestational Diabetes

0.040

GeneticVariation

BEFREE

This study strongly suggests that GCKR rs780094-C is associated with increased risk of GDM.

29410004

2018

Gestational Diabetes

CUI:	C0085207
Disease:	Gestational Diabetes

0.040

GeneticVariation

BEFREE

Carriers of the C allele of rs780094 were 1.41 (odds ratio, 95% CI, 0.97-2.03) times more likely to develop GDM.

27554451

2017