rs780094, GCKR

N. diseases: 62
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Metabolic Syndrome X
CUI: C0524620
Disease: Metabolic Syndrome X
0.830 GeneticVariation GWASCAT Multiple genotype-phenotype association study reveals intronic variant pair on SIDT2 associated with metabolic syndrome in a Korean population. 30382898 2018
Metabolic Syndrome X
CUI: C0524620
Disease: Metabolic Syndrome X
0.830 GeneticVariation GWASCAT New Common and Rare Variants Influencing Metabolic Syndrome and Its Individual Components in a Korean Population. 29632305 2018
Metabolic Syndrome X
CUI: C0524620
Disease: Metabolic Syndrome X
0.830 GeneticVariation BEFREE The intragenic rs1244979, rs2815752 in NEGR1 gene, and rs780094 in GCKR gene were genotyped and CNVs were determined by droplet digital polymerase chain reaction (ddPCR) in PCOS patients (n = 153) and controls without metabolic syndrome (n = 142). 27878529 2017
Metabolic Syndrome X
CUI: C0524620
Disease: Metabolic Syndrome X
0.830 GeneticVariation BEFREE The GCKR rs780094 polymorphism is associated with low HDL-C levels and MetS incidence in Taiwanese adolescents. 26799416 2016
Metabolic Syndrome X
CUI: C0524620
Disease: Metabolic Syndrome X
0.830 GeneticVariation GWASCAT Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits. 22399527 2012
Metabolic Syndrome X
CUI: C0524620
Disease: Metabolic Syndrome X
0.830 GeneticVariation GWASDB Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits. 22399527 2012
Metabolic Syndrome X
CUI: C0524620
Disease: Metabolic Syndrome X
0.830 GeneticVariation BEFREE Our results support that rs780094 and rs1260326 functional variants of the GCKR gene are inversely associated with serum triglycerides and fasting plasma glucose levels, as it was already reported for diabetic and metabolic syndrome patients in some other populations. 21114848 2010