rs780094, GCKR

N. diseases: 62
Disease: Steatohepatitis ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Steatohepatitis
CUI: C2711227
Disease: Steatohepatitis
0.030 GeneticVariation BEFREE PNPLA3 rs738409, GCKR rs780094 and TM6SF2 rs58542926 variants were independent risk factors of hepatic steatosis and elevated ALT levels. 29314568 2018
Steatohepatitis
CUI: C2711227
Disease: Steatohepatitis
0.030 GeneticVariation BEFREE We aimed to assess whether GCKR rs780094 C→T SNP influences the expression of steatosis, lobular inflammation and fibrosis in NAFLD patients, after correction for PNPLA3 genotype. 24498332 2014
Steatohepatitis
CUI: C2711227
Disease: Steatohepatitis
0.030 GeneticVariation BEFREE We used data from the National Health and Nutrition Examination Survey III to validate the association between rs738409 (PNPLA3), rs780094 (GCKR), and rs4240624 (PPP1R3B) with HS, with or without increased levels of ALT, among 3 different ancestries. 23416328 2013