rs7903146, TCF7L2

N. diseases: 93
Disease: Diabetic Nephropathy ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Diabetic Nephropathy
CUI: C0011881
Disease: Diabetic Nephropathy
0.030 GeneticVariation BEFREE The strong LD existed between the 2 single nucleotide polymorphisms and haplotype T-T (rs7903146-rs290487) increased the susceptibility to DN (OR = 2.63, 95% CI = 1.31-5.25).TCF7L2 rs7903146 polymorphism may be associated with the susceptibility to DN in Chinese Han population, but rs290487 is not. 30290587 2018
Diabetic Nephropathy
CUI: C0011881
Disease: Diabetic Nephropathy
0.030 GeneticVariation BEFREE Analysis of TCF7L2 rs7903146 in normal controls and diabetics with or without nephropathy demonstrated that the 'T' allele is associated with both diabetes (p = 0.049) and DN (p = 0.024), but this association is not independent of T2DM. 25185853 2014
Diabetic Nephropathy
CUI: C0011881
Disease: Diabetic Nephropathy
0.030 GeneticVariation BEFREE In our study the T allele of the rs7903146 SNP in the TCF7L2 gene confers the risk of developing diabetic nephropathy. 24574000 2014