rs7903146, TCF7L2

N. diseases: 93
Disease: Kidney Diseases ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Kidney Diseases
CUI: C0022658
Disease: Kidney Diseases
0.020 GeneticVariation BEFREE Analysis of TCF7L2 rs7903146 in normal controls and diabetics with or without nephropathy demonstrated that the 'T' allele is associated with both diabetes (p = 0.049) and DN (p = 0.024), but this association is not independent of T2DM. 25185853 2014
Kidney Diseases
CUI: C0022658
Disease: Kidney Diseases
0.020 GeneticVariation BEFREE An association was observed between rs7903146 and nephropathy (p<0.001), with 22% of TT homozygotes in this subgroup vs. 11% in patients without nephropathy (p=0.006, OR for TT 2.83, 95% CI 1.94-4.13). 21641671 2011