rs79658334, RET

N. diseases: 29
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Thyroid carcinoma
CUI: C0549473
Disease: Thyroid carcinoma
0.020 GeneticVariation BEFREE However, two gatekeeper mutations V804M and V804L in RET kinase domain have been frequently observed to cause drug resistance during the targeted therapy, largely limiting the application of reversible TKIs in TC. 27712045 2016
Thyroid carcinoma
CUI: C0549473
Disease: Thyroid carcinoma
0.020 GeneticVariation BEFREE A rapid method for the purification of wild-type and V804M mutant ret catalytic domain: A tool to study thyroid cancer. 16490247 2006