|
Neoplastic Syndromes, Hereditary
|
|
0.700 |
GeneticVariation
|
CLINVAR |
Determination of cancer risk associated with germ line BRCA1 missense variants by functional analysis.
|
17308087 |
2007 |
|
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
|
|
0.700 |
CausalMutation
|
CLINVAR |
A systematic genetic assessment of 1,433 sequence variants of unknown clinical significance in the BRCA1 and BRCA2 breast cancer-predisposition genes.
|
17924331 |
2007 |
|
Neoplastic Syndromes, Hereditary
|
|
0.700 |
GeneticVariation
|
CLINVAR |
Functional impact of missense variants in BRCA1 predicted by supervised learning.
|
17305420 |
2007 |
|
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
|
|
0.700 |
CausalMutation
|
CLINVAR |
Determination of cancer risk associated with germ line BRCA1 missense variants by functional analysis.
|
17308087 |
2007 |
|
Hereditary Breast and Ovarian Cancer Syndrome
|
|
0.700 |
CausalMutation
|
CLINVAR |
A systematic genetic assessment of 1,433 sequence variants of unknown clinical significance in the BRCA1 and BRCA2 breast cancer-predisposition genes.
|
17924331 |
2007 |
|
Hereditary Breast and Ovarian Cancer Syndrome
|
|
0.700 |
CausalMutation
|
CLINVAR |
Determination of cancer risk associated with germ line BRCA1 missense variants by functional analysis.
|
17308087 |
2007 |
|
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
|
|
0.700 |
CausalMutation
|
CLINVAR |
Application of embryonic lethal or other obvious phenotypes to characterize the clinical significance of genetic variants found in trans with known deleterious mutations.
|
16267036 |
2005 |
|
Hereditary Breast and Ovarian Cancer Syndrome
|
|
0.700 |
CausalMutation
|
CLINVAR |
Application of embryonic lethal or other obvious phenotypes to characterize the clinical significance of genetic variants found in trans with known deleterious mutations.
|
16267036 |
2005 |
|
Neoplastic Syndromes, Hereditary
|
|
0.700 |
GeneticVariation
|
CLINVAR |
Missense mutations in the BRCT domain of BRCA-1 from high-risk women frequently perturb strongly hydrophobic amino acids conserved among mammals.
|
15184261 |
2004 |
|
Malignant neoplasm of breast
|
|
0.700 |
GeneticVariation
|
UNIPROT |
Novel germline mutations in the BRCA1 and BRCA2 genes in Indian breast and breast-ovarian cancer families.
|
14722926 |
2004 |
|
Malignant neoplasm of breast
|
|
0.700 |
GeneticVariation
|
UNIPROT |
Structure and mechanism of BRCA1 BRCT domain recognition of phosphorylated BACH1 with implications for cancer.
|
15133502 |
2004 |
|
Neoplastic Syndromes, Hereditary
|
|
0.700 |
GeneticVariation
|
CLINVAR |
Structure-based assessment of missense mutations in human BRCA1: implications for breast and ovarian cancer predisposition.
|
15172985 |
2004 |
|
Malignant neoplasm of breast
|
|
0.700 |
GeneticVariation
|
UNIPROT |
Twenty-three novel BRCA1 and BRCA2 sequence alterations in breast and/or ovarian cancer families in Southern Germany.
|
12938098 |
2003 |
|
Malignant neoplasm of breast
|
|
0.700 |
GeneticVariation
|
UNIPROT |
Structural consequences of a cancer-causing BRCA1-BRCT missense mutation.
|
12427738 |
2003 |
|
Malignant neoplasm of breast
|
|
0.700 |
GeneticVariation
|
UNIPROT |
BRCA1 and BRCA2 mutation analysis of early-onset and familial breast cancer cases in Mexico.
|
12442275 |
2002 |
|
Malignant neoplasm of breast
|
|
0.700 |
GeneticVariation
|
UNIPROT |
BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function.
|
11301010 |
2001 |
|
Malignant neoplasm of breast
|
|
0.700 |
GeneticVariation
|
UNIPROT |
Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress.
|
11114888 |
2000 |
|
Malignant neoplasm of breast
|
|
0.700 |
GeneticVariation
|
UNIPROT |
Molecular characterization of germline mutations in the BRCA1 and BRCA2 genes from breast cancer families in Taiwan.
|
10323242 |
1999 |
|
Malignant neoplasm of breast
|
|
0.700 |
GeneticVariation
|
UNIPROT |
A high proportion of mutations in the BRCA1 gene in German breast/ovarian cancer families with clustering of mutations in the 3' third of the gene.
|
9760198 |
1998 |
|
Malignant neoplasm of breast
|
|
0.700 |
GeneticVariation
|
UNIPROT |
Constant denaturant gel electrophoresis (CDGE) in BRCA1 mutation screening.
|
9482581 |
1998 |
|
Malignant neoplasm of breast
|
|
0.700 |
GeneticVariation
|
UNIPROT |
Mutations in the BRCA1 gene in Japanese breast cancer patients.
|
8723683 |
1996 |
|
Malignant neoplasm of breast
|
|
0.700 |
GeneticVariation
|
UNIPROT |
Comparison of BRCA1 polymorphisms, rare sequence variants and/or missense mutations in unaffected and breast/ovarian cancer populations.
|
8776600 |
1996 |
|
Malignant neoplasm of breast
|
|
0.700 |
GeneticVariation
|
UNIPROT |
A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1.
|
7545954 |
1994 |
|
Malignant neoplasm of breast
|
|
0.700 |
GeneticVariation
|
UNIPROT |
Mutations in the BRCA1 gene in families with early-onset breast and ovarian cancer.
|
7894491 |
1994 |
|
Malignant neoplasm of breast
|
|
0.700 |
GeneticVariation
|
UNIPROT |
BRCA1 mutations in primary breast and ovarian carcinomas.
|
7939630 |
1994 |