rs8099917, None

N. diseases: 60
Disease: Liver Cirrhosis ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Liver Cirrhosis
CUI: C0023890
Disease: Liver Cirrhosis
0.030 GeneticVariation BEFREE Multivariate analysis of SVR predictors in patients with HCV genotype-1 infection included age (<24 years), BMI (<25), absence of cirrhosis, HCV RNA level (<400 000 IU/mL), rs8099917 TT and rs12979860 CC, all of which were associated with a higher SVR rate. 27735085 2017
Liver Cirrhosis
CUI: C0023890
Disease: Liver Cirrhosis
0.030 GeneticVariation BEFREE Multivariable analysis identified four independent factors that were significantly associated with SVR: IL28B SNP rs8099917 genotype (P = 6.90 × 10(-5) ), pre-existence of cirrhosis (P = 3.99 × 10(-3) ), prior treatment response (P = 0.0126), and rapid virological response (P = 0.0239). 24117654 2014
Liver Cirrhosis
CUI: C0023890
Disease: Liver Cirrhosis
0.030 GeneticVariation BEFREE The T/T genotype of rs8099917 was not associated with the development of HCC (p = 0.623), although stepwise logistic regression analysis showed that liver cirrhosis, age greater than 68 years, and serum albumin <4.2 mg/dl were associated with HCC onset. 22245236 2012