rs8099917, None

N. diseases: 60
Disease: Mixed cryoglobulinemia ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Mixed cryoglobulinemia
CUI: C0543697
Disease: Mixed cryoglobulinemia
0.030 GeneticVariation BEFREE In the logistic regression analysis baseline viral load >600.000 IU/ml (p < 001), IL28B rs8099917/rs12979860 TT/CC (p < 0.001), NT5 (gene encoding for 5' nucleotidase) 153 TC (p = 0.012) and ABCB1 3435 CT/TT (p = 0.034) genotypes predicted MC presence. 28453396 2017
Mixed cryoglobulinemia
CUI: C0543697
Disease: Mixed cryoglobulinemia
0.030 GeneticVariation BEFREE IL28B rs8099917/rs12979860 is useful in the treatment of MC-positive HCV patients with PEG-IFN and ribavirin; the TT/CC genotype is associated with SVR, the TG/TC with non-SVR; TT/CC is also predictive of MC in HCV patients. 26060059 2015
Mixed cryoglobulinemia
CUI: C0543697
Disease: Mixed cryoglobulinemia
0.030 GeneticVariation BEFREE The rs12979860/rs8099917 IL28B polymorphisms were analysed in 481 consecutive HCV-positive subjects (250 with MC and 231 without MC, as controls) using real-time PCR and direct sequencing. 23490377 2013