rs861539, KLC1;XRCC3

N. diseases: 104
Disease: Oral Submucous Fibrosis ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Oral Submucous Fibrosis
CUI: C0029172
Disease: Oral Submucous Fibrosis
0.010 GeneticVariation BEFREE Gene-gene interaction analysis by multifactor dimensionality reduction (MDR) revealed that XRCC3 Thr 241 Met had the largest univariate effect followed by XRCC3 Thr 241 Met - NAT2 A857G in men that presents a highly synergistic interaction as one of the potential combinations of single nucleotide polymorphisms (SNPs) to increase the risk of OSF in men if exposed to arecanut or smokeless tobacco usage. 22092501 2012