rs861539, KLC1;XRCC3

N. diseases: 104
Disease: Thyroid carcinoma ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Thyroid carcinoma
CUI: C0549473
Disease: Thyroid carcinoma
0.020 GeneticVariation BEFREE CONCLUSIONS We conclude that the XRCC3 Thr241Met</span> polymorphism is associated with an increased risk of thyroid cancer in the overall population, while no significant association was observed in individual ethnic subgroups due to limited population size. 26687776 2015
Thyroid carcinoma
CUI: C0549473
Disease: Thyroid carcinoma
0.020 GeneticVariation BEFREE Additionaly, when the XRCC3 T241M data were analyzed concerning the presence of at least one wild-type allele, we observed that individuals homozygous for the variant allele had a higher risk for thyroid cancer (adjusted OR = 2.0; confidence interval 95%: 1.1-3.6; p = 0.026). 19772428 2009