rs878854066, TP53

N. diseases: 213
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Endometrial Carcinoma
CUI: C0476089
Disease: Endometrial Carcinoma
0.080 GeneticVariation BEFREE The aim of the study was to determine an association of TP53 codon 72 (Arg72Pro, G>C transversion, rs1042522) and MDM2 SNP309 (T>G change, rs2279744) polymorphisms in endometrial cancer (EC) of postmenopausal women, regarding grading and staging of EC. 25316267 2014
Endometrial Carcinoma
CUI: C0476089
Disease: Endometrial Carcinoma
0.080 GeneticVariation BEFREE Association of MDM2 SNP309 and TP53 Arg72Pro polymorphisms with risk of endometrial cancer. 23624782 2013
Endometrial Carcinoma
CUI: C0476089
Disease: Endometrial Carcinoma
0.080 GeneticVariation BEFREE Genotype misclassification in genetic association studies of the rs1042522 TP53 (Arg72Pro) polymorphism: a systematic review of studies of breast, lung, colorectal, ovarian, and endometrial cancer. 23729685 2013
Endometrial Carcinoma
CUI: C0476089
Disease: Endometrial Carcinoma
0.080 GeneticVariation BEFREE The aim of this study was to detect TP53 Arg72Pro polymorphism in postmenopausal patients with endometrial cancer (EC), to evaluate the risk of EC connected with it, as well to check for possible relationships with staging, grading and some risk factors of this neoplasm. 24379271 2013
Endometrial Carcinoma
CUI: C0476089
Disease: Endometrial Carcinoma
0.080 GeneticVariation BEFREE It has been suggested that the p53 tumor suppressor gene Arg72Pro polymorphism is associated with endometrial cancer. 22277327 2012
Endometrial Carcinoma
CUI: C0476089
Disease: Endometrial Carcinoma
0.080 GeneticVariation BEFREE In conclusion, we did not observe any evidence for a role of TP53 Arg72Pro polymorphism in endometrial cancer. 20552298 2011
Endometrial Carcinoma
CUI: C0476089
Disease: Endometrial Carcinoma
0.080 GeneticVariation BEFREE Our data did not demonstrate any significant difference in the prevalence of the p53 Arg72Pro genotype between patients and controls, providing evidence that this polymorphism is only weakly associated with the risk of endometrial cancer and prognostic factors in Caucasian women. 19209008 2009
Endometrial Carcinoma
CUI: C0476089
Disease: Endometrial Carcinoma
0.080 GeneticVariation BEFREE Association of p73 G4C14-to-A4T14 polymorphism at exon 2 and p53 Arg72Pro polymorphism with the risk of endometrial cancer in Japanese subjects. 15723718 2005