rs878854066, TP53

N. diseases: 213
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
cervical cancer
CUI: C4048328
Disease: cervical cancer
0.100 GeneticVariation BEFREE Combined analysis revealed that the genotypes of rs4938723 CT/CC and TP53 Arg72Pro CG/CC had an increased cervical cancer risk (OR = 2.21, 95 % CI = 1.38-3.53). 26619844 2016
cervical cancer
CUI: C4048328
Disease: cervical cancer
0.100 GeneticVariation BEFREE A hundred HIV-infected women were examined for HPV detection and its genotypes, as well as the frequencies of the SNPs Arg72Pro and SNP309 and their associations with CC risk factors. 25181402 2015
cervical cancer
CUI: C4048328
Disease: cervical cancer
0.100 GeneticVariation BEFREE The Arg variant of p53 Arg72Pro is associated with progression of SIL to cervical cancer only in the presence of HPV positivity. 23065429 2012
cervical cancer
CUI: C4048328
Disease: cervical cancer
0.100 GeneticVariation BEFREE The aim of this Human Genome Epidemiology (HuGE) review and meta-analysis was to derive a more precise estimation of the association between p53 codon 72 polymorphism (Arg72Pro, rs1042522 G>C) and cervical cancer risk among Asians. 23244080 2012
cervical cancer
CUI: C4048328
Disease: cervical cancer
0.100 GeneticVariation BEFREE These results suggest that a heterozygous TP53 Arg72Pro genotype may contribute to cervical cancer susceptibility. 21665181 2011
cervical cancer
CUI: C4048328
Disease: cervical cancer
0.100 GeneticVariation BEFREE To better understand the role of this polymorphism in cervical cancer etiology, we investigated the association between p53 R72P and cervical cancer risk in Chinese women from southern Han. 20193851 2010
cervical cancer
CUI: C4048328
Disease: cervical cancer
0.100 GeneticVariation BEFREE Driven by findings that human papillomavirus (HPV)-induced degradation of p53 differs by a TP53 polymorphism at codon 72 (Pro72Arg), past studies of TP53 genetic variants and cervical cancer have focused on this nonsynonymous polymorphism, with mixed results. 19423538 2009
cervical cancer
CUI: C4048328
Disease: cervical cancer
0.100 GeneticVariation BEFREE The p53 R72P polymorphism does not influence cervical cancer development in a Portuguese population: a study in exfoliated cervical cells. 18205229 2008
cervical cancer
CUI: C4048328
Disease: cervical cancer
0.100 GeneticVariation BEFREE Genetic polymorphisms of p73 G4C14-to-A4T14 at exon 2 and p53 Arg72Pro and the risk of cervical cancer in Japanese. 15036661 2004
cervical cancer
CUI: C4048328
Disease: cervical cancer
0.100 GeneticVariation BEFREE We failed to confirm earlier reports of increased cervical cancer susceptibility in women who harbor the p53 P72R allele. 12142377 2002