|
Stomach Carcinoma
|
|
0.060 |
GeneticVariation
|
BEFREE |
In conclusion, we were the first to show that a common polymorphism (rs895819) in hsa-mir-27a, by modulating miR-27a and ZBTB10 levels, acted as an important factor of the gastric cancer susceptibility.
|
20666778 |
2010 |
|
Malignant neoplasm of stomach
|
|
0.060 |
GeneticVariation
|
BEFREE |
In conclusion, we were the first to show that a common polymorphism (rs895819) in hsa-mir-27a, by modulating miR-27a and ZBTB10 levels, acted as an important factor of the gastric cancer susceptibility.
|
20666778 |
2010 |
|
Breast Cancer, Familial
|
|
0.010 |
GeneticVariation
|
BEFREE |
We hypothesize that the G-variant of rs895819 might impair the maturation of the oncogenic miR-27a and thus, is associated with familial breast cancer risk.
|
19921425 |
2010 |
|
Malignant neoplasm of breast
|
|
0.100 |
GeneticVariation
|
BEFREE |
To explore the relevance of miRNA polymorphisms and female physiological characteristics to breast cancer risk, SNPs located within hsa-miR-605 (rs2043556), hsa-miR-149 (rs2292832), hsa-miR-27a (rs895819), hsa-miR-196a-2 (rs11614913) and hsa-miR-618 (rs2682818) were selected, and their associations with breast cancer risk were analysed.
|
22074121 |
2012 |
|
Colorectal Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Our data suggest a lack of association between rs11614913, rs895819 and rs2910164 and colorectal cancer risk in the Central-European Caucasian population, a population with an extremely high incidence of sporadic colorectal cancer.
|
22719192 |
2012 |
|
Breast Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
These findings suggest that hsa-mir-27a rs895819 polymorphism may play an important role in breast cancer development.
|
23464432 |
2012 |
|
Malignant neoplasm of breast
|
|
0.100 |
GeneticVariation
|
BEFREE |
These findings suggest that hsa-mir-27a rs895819 polymorphism may play an important role in breast cancer development.
|
23464432 |
2012 |
|
Breast Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
To explore the relevance of miRNA polymorphisms and female physiological characteristics to breast cancer risk, SNPs located within hsa-miR-605 (rs2043556), hsa-miR-149 (rs2292832), hsa-miR-27a (rs895819), hsa-miR-196a-2 (rs11614913) and hsa-miR-618 (rs2682818) were selected, and their associations with breast cancer risk were analysed.
|
22074121 |
2012 |
|
Malignant neoplasm of colon and/or rectum
|
|
0.060 |
GeneticVariation
|
BEFREE |
Our data suggest a lack of association between rs11614913, rs895819 and rs2910164 and colorectal cancer risk in the Central-European Caucasian population, a population with an extremely high incidence of sporadic colorectal cancer.
|
22719192 |
2012 |
|
Carcinogenesis
|
|
0.030 |
GeneticVariation
|
BEFREE |
Inhibitory effect of minor allele T of rs2071504 SNP within the exon of POLR2A gene was significantly associated with gastric carcinogenesis (p = 0.033, aOR = 0.742, 95%CI = 0.564-0.977) and the SNP rs895819 in the miR-27a gene with the minor allele C presented significantly reduced risk to gastric cancer (p = 0.037, aOR = 0.771, 95%CI = 0.604-0.985).
|
22350505 |
2012 |
|
Non-Small Cell Lung Carcinoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
Five SNPs found in pre-miRNAs (rs11614913/miR-196a2, rs2910164/miR-146a, rs6505162/miR-423, rs2289030/miR-492, and rs895819/miR-27a) and 2 SNPs found in pri-miRNAs (rs7372209/miR-26a-1 and rs213210/miR-219-1) were genotyped in 388 patients with NSCLC.
|
22818121 |
2012 |
|
Renal Cell Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our results suggest that the pre-miR-27a rs895819 polymorphism can predict RCC risk in a Chinese population.
|
23118855 |
2012 |
|
Hypertensive disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
We also observed that rs895819 had multiplicative interactions with age and hypertension.
|
23118855 |
2012 |
|
Breast Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
This meta-analysis suggests that the pre-miR-27a rs895819 polymorphism may contribute to the susceptibilities of some specific-type of cancers, including breast cancer, renal cell cancer, nasopharyngeal cancer and digestive tract cancers, as well as the susceptibilities of cancers in Caucasians to some extent.
|
23762318 |
2013 |
|
Primary malignant neoplasm
|
|
0.100 |
GeneticVariation
|
BEFREE |
Pre-miR-27a rs895819A/G polymorphisms in cancer: a meta-analysis.
|
23762318 |
2013 |
|
Malignant Neoplasms
|
|
0.100 |
GeneticVariation
|
BEFREE |
This meta-analysis suggests that the pre-miR-27a rs895819 polymorphism may contribute to the susceptibilities of some specific-type of cancers, including breast cancer, renal cell cancer, nasopharyngeal cancer and digestive tract cancers, as well as the susceptibilities of cancers in Caucasians to some extent.
|
23762318 |
2013 |
|
Malignant neoplasm of breast
|
|
0.100 |
GeneticVariation
|
BEFREE |
This meta-analysis suggests that the pre-miR-27a rs895819 polymorphism may contribute to the susceptibilities of some specific-type of cancers, including breast cancer, renal cell cancer, nasopharyngeal cancer and digestive tract cancers, as well as the susceptibilities of cancers in Caucasians to some extent.
|
23762318 |
2013 |
|
Breast Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
The findings suggest that pre-mir-27a rs895819 polymorphism may have some relation to breast cancer susceptibility or cancer development in Caucasian.
|
23266669 |
2013 |
|
Malignant neoplasm of breast
|
|
0.100 |
GeneticVariation
|
BEFREE |
Moreover, significant associations between the presence of rs895819 and the histological grade and estrogen status of breast cancers were observed among the older group.
|
23954879 |
2013 |
|
Primary malignant neoplasm
|
|
0.100 |
GeneticVariation
|
BEFREE |
This meta-analysis indicated that the hsa-miR-27a rs895819</span> polymorphism did not correlate with overall cancer risk in the general population.
|
23524006 |
2013 |
|
Malignant neoplasm of breast
|
|
0.100 |
GeneticVariation
|
BEFREE |
The findings suggest that pre-mir-27a rs895819 polymorphism may have some relation to breast cancer susceptibility or cancer development in Caucasian.
|
23266669 |
2013 |
|
Malignant Neoplasms
|
|
0.100 |
GeneticVariation
|
BEFREE |
The results of the overall meta-analysis did not suggest any associations between pre-mir-27a rs895819 polymorphism and canc</span>er susceptibility.
|
23266669 |
2013 |
|
Malignant Neoplasms
|
|
0.100 |
GeneticVariation
|
BEFREE |
Previous studies have investigated the role of rs895819 in cancer risk, but the results remain contradictory, rather than conclusive.
|
23954879 |
2013 |
|
Malignant Neoplasms
|
|
0.100 |
GeneticVariation
|
BEFREE |
Pre-miR-27a rs895819A/G polymorphisms in cancer: a meta-analysis.
|
23762318 |
2013 |
|
Malignant Neoplasms
|
|
0.100 |
GeneticVariation
|
BEFREE |
This meta-analysis indicated that the hsa-miR-27a rs895819</span> polymorphism did not correlate with overall cancer risk in the general population.
|
23524006 |
2013 |