|
Liver carcinoma
|
|
0.840 |
GeneticVariation
|
BEFREE |
We found that rs2856718 and rs9275572 in HLA-DQ significantly decreased HBV-related HCC in total population, especially in Chinese, but not in Saudi Arabian.
|
28761441 |
2017 |
|
Liver carcinoma
|
|
0.840 |
GeneticVariation
|
BEFREE |
The AG/GG genotype of rs9275572 and HLA-DQB1 Block2 CCCCC haplotype may have protective effects in HBV-related HCC patients receiving hepatic resection.
|
27288300 |
2016 |
|
Liver carcinoma
|
|
0.840 |
GeneticVariation
|
BEFREE |
Our study suggested that HLA-DQ loci (rs9</span>275572) were associated with HBV-related HCC as a protective factor in Han Chinese.
|
27209411 |
2016 |
|
Liver carcinoma
|
|
0.840 |
GeneticVariation
|
BEFREE |
Two recent genome-wide studies showed that the single-nucleotide polymorphisms in the HLA-DQ region (rs2856718 and rs9275572) were associated with chronic hepatitis B virus infection and chronic hepatitis C virus-associated hepatocellular carcinoma in Japanese patients.
|
24750255 |
2014 |
|
Liver carcinoma
|
|
0.840 |
GeneticVariation
|
GWASDB |
Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus-related hepatocellular carcinoma.
|
23242368 |
2013 |
|
Liver carcinoma
|
|
0.840 |
GeneticVariation
|
GWASCAT |
Genome-wide association study identifies a susceptibility locus for HCV-induced hepatocellular carcinoma.
|
21499248 |
2011 |
|
Liver carcinoma
|
|
0.840 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies a susceptibility locus for HCV-induced hepatocellular carcinoma.
|
21499248 |
2011 |
|
Lupus Erythematosus, Systemic
|
|
0.810 |
GeneticVariation
|
BEFREE |
The IRF5-TNPO3 region showed the strongest association and largest OR for SLE (rs10488631: genomic control-adjusted P [Pgcadj ] = 2.61 × 10(-29), OR 2.12 [95% CI 1.88-2.39]), followed by HLA class II on the DQA2-DQB1 loci (rs9275572: Pgcadj = 1.11 × 10(-16), OR 1.62 [95% CI 1.46-1.80] and rs9271366: Pgcadj = 6.46 × 10(-12), OR 2.06 [95% CI 1.71-2.50]).
|
26606652 |
2016 |
|
Lupus Erythematosus, Systemic
|
|
0.810 |
GeneticVariation
|
GWASDB |
GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.
|
24871463 |
2014 |
|
Lupus Erythematosus, Systemic
|
|
0.810 |
GeneticVariation
|
GWASCAT |
GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.
|
24871463 |
2014 |
|
Lupus Erythematosus, Systemic
|
|
0.810 |
GeneticVariation
|
GWASDB |
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.
|
18204446 |
2008 |
|
Hepatitis C, Chronic
|
|
0.800 |
GeneticVariation
|
GWASDB |
HLA-DQB1*03 confers susceptibility to chronic hepatitis C in Japanese: a genome-wide association study.
|
24376798 |
2013 |
|
Hepatitis C, Chronic
|
|
0.800 |
GeneticVariation
|
GWASCAT |
HLA-DQB1*03 confers susceptibility to chronic hepatitis C in Japanese: a genome-wide association study.
|
24376798 |
2013 |
|
Alopecia Areata
|
|
0.800 |
GeneticVariation
|
GWASDB |
Genome-wide pooling approach identifies SPATA5 as a new susceptibility locus for alopecia areata.
|
22027810 |
2012 |
|
Alopecia Areata
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genome-wide association study in alopecia areata implicates both innate and adaptive immunity.
|
20596022 |
2010 |
|
Alopecia Areata
|
|
0.800 |
GeneticVariation
|
GWASDB |
Genome-wide association study in alopecia areata implicates both innate and adaptive immunity.
|
20596022 |
2010 |
|
Crohn Disease
|
|
0.700 |
GeneticVariation
|
GWASDB |
A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population.
|
23266558 |
2013 |
|
Lymphoma, Follicular
|
|
0.700 |
GeneticVariation
|
GWASDB |
GWAS of follicular lymphoma reveals allelic heterogeneity at 6p21.32 and suggests shared genetic susceptibility with diffuse large B-cell lymphoma.
|
21533074 |
2011 |
|
Rheumatoid Arthritis
|
|
0.700 |
GeneticVariation
|
GWASDB |
A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis.
|
21156761 |
2011 |
|
Narcolepsy
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide association database developed in the Japanese Integrated Database Project.
|
19629137 |
2009 |
|
Rheumatoid Arthritis
|
|
0.700 |
GeneticVariation
|
GWASDB |
TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study.
|
17804836 |
2007 |
|
Multiple Sclerosis
|
|
0.700 |
GeneticVariation
|
GWASDB |
Risk alleles for multiple sclerosis identified by a genomewide study.
|
17660530 |
2007 |
|
Hepatitis C
|
|
0.020 |
GeneticVariation
|
BEFREE |
Several recent genome-wide studies showed that the genetic polymorphisms in the HLA-DQ region (rs9275572 and rs2856718) were related to chronic hepatitis B virus (HBV) infection and chronic hepatitis C virus (HCV)-associated hepatocellular carcinoma (HCC).
|
27209411 |
2016 |
|
Hepatitis B
|
|
0.020 |
GeneticVariation
|
BEFREE |
Several recent genome-wide studies showed that the genetic polymorphisms in the HLA-DQ region (rs9275572 and rs2856718) were related to chronic hepatitis B virus (HBV) infection and chronic hepatitis C virus (HCV)-associated hepatocellular carcinoma (HCC).
|
27209411 |
2016 |
|
Hepatitis B
|
|
0.020 |
GeneticVariation
|
BEFREE |
The results showed that rs2856718, rs3077, rs9277535 and rs9275572 were associated with HBV infection (p = 0.0003, OR = 1.351, CI = 1.147-1.591; p = 0.041, OR = 1.20, CI = 1.007-1.43; p = 0.045, OR = 1.198, CI = 1.004-1.43 and p = 0.0018, OR = 0.776, CI = 0.662-0.910, respectively).
|
24465366 |
2014 |