|
Hypertriglyceridemia
|
|
0.830 |
GeneticVariation
|
BEFREE |
Sixteen SNPs were significantly associated with an increased risk of HTG development, with odds ratios (ORs) (95% confidence interval [CI]) varying from 1.40 (1.01-1.95) to 4.69 (3.29-6.68) (rs964184 within the APOA5 gene).
|
31222479 |
2019 |
|
Coronary heart disease
|
|
0.830 |
GeneticVariation
|
BEFREE |
Our results indicate that both gender and age have great impacts on the association of the rs964184 polymorphism with CHD among Chinese.
|
29339699 |
2018 |
|
Hypertriglyceridemia
|
|
0.830 |
GeneticVariation
|
GWASCAT |
A common variant association study in ethnic Saudi Arabs reveals novel susceptibility loci for hypertriglyceridemia.
|
27599772 |
2017 |
|
Coronary heart disease
|
|
0.830 |
GeneticVariation
|
GWASCAT |
Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
|
27790247 |
2016 |
|
Hypertriglyceridemia
|
|
0.830 |
GeneticVariation
|
BEFREE |
Multivariate logistic regression analysis with adjustment for age, gender and body mass index revealed that rs964184 of ZPR1 (P=5.1x10‑7; odds ratio, 1.37; dominant model), rs4845625 of IL6R (P=0.0019, odds ratio, 1.25; dominant model) and rs46522 of UBE2Z (P=0.0039, odds ratio, 1.19; dominant model) were significantly associated with hypertriglyceridemia, and that rs599839 of PSRC1 (P=0.0004, odds ratio, 0.70; dominant model) and rs2075650 of TOMM40 (P=0.0004, odds ratio, 1.43; dominant model) were significantly associated with hyper‑LDL‑cholesterolemia.
|
26238946 |
2015 |
|
Coronary heart disease
|
|
0.830 |
GeneticVariation
|
BEFREE |
MG 18∶2 showed an enrichment (P-value = 0.002) of significant associations with CHD-associated SNPs (P-value = 1.2×10-7 for association with rs964184 in the ZNF259/APOA5 region) and a weak, but positive causal effect (odds ratio = 1.05 per SD increment in MG 18∶2, P-value = 0.05) on CHD, as suggested by Mendelian randomization analysis.
|
25502724 |
2014 |
|
Coronary heart disease
|
|
0.830 |
GeneticVariation
|
GWASCAT |
Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.
|
24262325 |
2014 |
|
Hypertriglyceridemia
|
|
0.830 |
GeneticVariation
|
BEFREE |
The G-G-A-A-C-C haplotype, carrying rs964184-G-allele, was associated with increased risk of HCH (OR: 1.35, 95% CI: 1.10, 1.66, P = 0.005) and HTG (OR: 1.75, 95% CI: 1.39, 2.21, P = 0.000).
|
24780069 |
2014 |
|
Hypertriglyceridemia
|
|
0.830 |
GeneticVariation
|
GWASDB |
Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci.
|
23505323 |
2013 |
|
Coronary heart disease
|
|
0.830 |
GeneticVariation
|
BEFREE |
Recently, the rs964184 polymorphism has been associated with coronary artery disease in nonrheumatic Caucasian individuals.
|
24131021 |
2013 |
|
Coronary heart disease
|
|
0.830 |
GeneticVariation
|
GWASDB |
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.
|
21378990 |
2011 |
|
Coronary heart disease
|
|
0.830 |
GeneticVariation
|
GWASDB |
Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.
|
21347282 |
2011 |
|
Coronary heart disease
|
|
0.830 |
GeneticVariation
|
GWASCAT |
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.
|
21378990 |
2011 |
|
Hypertriglyceridemia
|
|
0.830 |
GeneticVariation
|
GWASDB |
Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia.
|
20657596 |
2010 |
|
Hypertriglyceridemia
|
|
0.830 |
GeneticVariation
|
GWASCAT |
Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia.
|
20657596 |
2010 |
|
Metabolic Syndrome X
|
|
0.810 |
GeneticVariation
|
GWASCAT |
A previously known lipid locus, APOA1/C3/A4/A5 gene cluster region (SNP rs964184), was associated with MetS in all 4 study samples (P=7.23×10(-9) in meta-analysis).
|
22399527 |
2012 |
|
Metabolic Syndrome X
|
|
0.810 |
GeneticVariation
|
GWASDB |
A previously known lipid locus, APOA1/C3/A4/A5 gene cluster region (SNP rs964184), was associated with MetS in all 4 study samples (P=7.23×10(-9) in meta-analysis).
|
22399527 |
2012 |
|
Metabolic Syndrome X
|
|
0.810 |
GeneticVariation
|
BEFREE |
A previously known lipid locus, APOA1/C3/A4/A5 gene cluster region (SNP rs964184), was associated with MetS in all 4 study samples (P=7.23×10(-9) in meta-analysis).
|
22399527 |
2012 |
|
High density lipoprotein measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genetic analyses of diverse populations improves discovery for complex traits.
|
31217584 |
2019 |
|
Triglycerides measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genetic analyses of diverse populations improves discovery for complex traits.
|
31217584 |
2019 |
|
Serum total cholesterol measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genetic analyses of diverse populations improves discovery for complex traits.
|
31217584 |
2019 |
|
Triglycerides measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genetic architecture of human plasma lipidome and its link to cardiovascular disease.
|
31551469 |
2019 |
|
Triglycerides measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genome-wide association study of blood lipids in Indians confirms universality of established variants.
|
30911093 |
2019 |
|
High density lipoprotein measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genome-wide association study of blood lipids in Indians confirms universality of established variants.
|
30911093 |
2019 |
|
High density lipoprotein measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
|
30926973 |
2019 |