Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4322
Gene Symbol: MMP13
MMP13
matrix metallopeptidase 13 0.452 0.923 7.9E-18
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.200 None 0.983 6 0 1996 2020
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
interleukin 1 beta 0.276 0.962 0.13
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.400 None 0.997 5 0 1992 2020
Entrez Id: 11096
Gene Symbol: ADAMTS5
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif 5 0.597 0.654 8.0E-07
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.100 None 0.962 4 0 2002 2020
Entrez Id: 54829
Gene Symbol: ASPN
ASPN
asporin 0.636 0.500 1.0E-07
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.400 None 0.931 4 0 2005 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.231 0.962 0.80
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.100 None 0.989 3 0 1989 2020
Entrez Id: 4312
Gene Symbol: MMP1
MMP1
matrix metallopeptidase 1 0.385 0.885 7.7E-18
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.100 None 0.975 3 0 1996 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.248 0.962 0.32
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.100 None 1.000 3 0 1990 2020
Entrez Id: 8200
Gene Symbol: GDF5
GDF5
growth differentiation factor 5 0.511 0.692 0.67
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.400 None 0.960 3 0 2007 2019
Entrez Id: 9507
Gene Symbol: ADAMTS4
ADAMTS4
ADAM metallopeptidase with thrombospondin type 1 motif 4 0.582 0.692 2.0E-06
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.100 None 0.971 3 0 2002 2020
Entrez Id: 51314
Gene Symbol: NME8
NME8
NME/NM23 family member 8 0.644 0.692 5.6E-28
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.020 None 1.000 2 0 2006 2007
Entrez Id: 10563
Gene Symbol: CXCL13
CXCL13
C-X-C motif chemokine ligand 13 0.472 0.731 0.83
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.030 None 1.000 2 0 2001 2008
Entrez Id: 653
Gene Symbol: BMP5
BMP5
bone morphogenetic protein 5 0.653 0.577 9.0E-04
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.060 None 1.000 2 0 2006 2019
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
hypoxia inducible factor 1 subunit alpha 0.327 0.923 0.98
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.100 None 1.000 2 0 2003 2019
Entrez Id: 2487
Gene Symbol: FRZB
FRZB
frizzled related protein 0.573 0.654 1.1E-03
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.400 None 0.923 2 0 1998 2019
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
endothelin 1 0.380 0.846 0.46
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.050 None 1.000 2 0 1999 2016
Entrez Id: 6387
Gene Symbol: CXCL12
CXCL12
C-X-C motif chemokine ligand 12 0.379 0.846 0.12
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.100 None 0.955 2 0 2002 2019
Entrez Id: 177
Gene Symbol: AGER
AGER
advanced glycosylation end-product specific receptor 0.420 0.885 6.4E-16
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.400 None 1.000 2 0 2005 2019
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
transforming growth factor beta 1 0.287 0.962 3.7E-02
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.500 None 1.000 2 0 2000 2020
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
nitric oxide synthase 2 0.364 0.923 4.0E-15
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.050 None 1.000 2 0 2007 2019
Entrez Id: 1280
Gene Symbol: COL2A1
COL2A1
collagen type II alpha 1 chain 0.444 0.846 1.00
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.500 None 0.941 2 0 1993 2020
Entrez Id: 1311
Gene Symbol: COMP
COMP
cartilage oligomeric matrix protein 0.503 0.808 1.3E-09
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.500 None 0.971 2 0 1995 2019
Entrez Id: 388
Gene Symbol: RHOB
RHOB
ras homolog family member B 0.653 0.423 0.12
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.020 None 1.000 2 0 2006 2007
Entrez Id: 3077
Gene Symbol: HFE
HFE
homeostatic iron regulator 0.436 0.846 2.6E-08
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.080 None 1.000 2 0 2003 2018
Entrez Id: 5590
Gene Symbol: PRKCZ
PRKCZ
protein kinase C zeta 0.604 0.654 0.54
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.020 None 1.000 2 0 2007 2008
Entrez Id: 8600
Gene Symbol: TNFSF11
TNFSF11
TNF superfamily member 11 0.453 0.846 4.9E-03
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.100 None 1.000 2 0 2000 2019