Source: ANIMAL_MODELS

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3689
Gene Symbol: ITGB2
ITGB2
integrin subunit beta 2 0.444 0.923 5.1E-15
CUI: C0242488
Disease: Acute Lung Injury
Acute Lung Injury
disease 0.200 None 1.000 1 0 1992 1992
Entrez Id: 2936
Gene Symbol: GSR
GSR
glutathione-disulfide reductase 0.494 0.846 1.3E-06
CUI: C0242488
Disease: Acute Lung Injury
Acute Lung Injury
disease 0.200 None 1.000 1 0 1994 1994
Entrez Id: 6372
Gene Symbol: CXCL6
CXCL6
C-X-C motif chemokine ligand 6 0.582 0.692 2.7E-09
CUI: C0242488
Disease: Acute Lung Injury
Acute Lung Injury
disease 0.200 None 1.000 1 0 1995 1995
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
interleukin 1 beta 0.276 0.962 0.13
CUI: C0242488
Disease: Acute Lung Injury
Acute Lung Injury
disease 0.210 None 1.000 4 0 1996 2012
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
interleukin 1 receptor antagonist 0.373 0.923 3.1E-02
CUI: C0242488
Disease: Acute Lung Injury
Acute Lung Injury
disease 0.200 None 1.000 2 0 1996 2005
Entrez Id: 7432
Gene Symbol: VIP
VIP
vasoactive intestinal peptide 0.437 0.846 4.2E-04
CUI: C0242488
Disease: Acute Lung Injury
Acute Lung Injury
disease 0.500 None 1.000 1 0 1996 2010
Entrez Id: 7498
Gene Symbol: XDH
XDH
xanthine dehydrogenase 0.529 0.846 2.6E-22
CUI: C0242488
Disease: Acute Lung Injury
Acute Lung Injury
disease 0.200 None 1.000 1 0 1998 1998
Entrez Id: 6590
Gene Symbol: SLPI
SLPI
secretory leukocyte peptidase inhibitor 0.449 0.846 9.0E-04
CUI: C0242488
Disease: Acute Lung Injury
Acute Lung Injury
disease 0.200 None 1.000 2 0 1999 2015
Entrez Id: 7077
Gene Symbol: TIMP2
TIMP2
TIMP metallopeptidase inhibitor 2 0.425 0.846 0.79
CUI: C0242488
Disease: Acute Lung Injury
Acute Lung Injury
disease 0.200 None 1.000 1 0 1999 1999
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.231 0.962 0.80
CUI: C0242488
Disease: Acute Lung Injury
Acute Lung Injury
disease 0.200 None 1.000 3 0 2000 2012
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
serpin family E member 1 0.359 0.885 4.4E-02
CUI: C0242488
Disease: Acute Lung Injury
Acute Lung Injury
disease 0.200 None 1.000 3 0 2000 2015
Entrez Id: 6351
Gene Symbol: CCL4
CCL4
C-C motif chemokine ligand 4 0.466 0.923 0.24
CUI: C0242488
Disease: Acute Lung Injury
Acute Lung Injury
disease 0.200 None 1.000 2 0 2000 2012
Entrez Id: 1991
Gene Symbol: ELANE
ELANE
elastase, neutrophil expressed 0.447 0.846 1.2E-03
CUI: C0242488
Disease: Acute Lung Injury
Acute Lung Injury
disease 0.200 None 1.000 3 0 2004 2008
Entrez Id: 3596
Gene Symbol: IL13
IL13
interleukin 13 0.386 0.846 1.4E-02
CUI: C0242488
Disease: Acute Lung Injury
Acute Lung Injury
disease 0.200 None 1.000 1 0 2004 2004
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
cytochrome P450 family 1 subfamily A member 1 0.436 0.846 1.1E-17
CUI: C0242488
Disease: Acute Lung Injury
Acute Lung Injury
disease 0.200 None 1.000 1 0 2006 2006
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
peroxisome proliferator activated receptor gamma 0.358 0.885 2.9E-02
CUI: C0242488
Disease: Acute Lung Injury
Acute Lung Injury
disease 0.500 None 1.000 1 0 2006 2011
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
nitric oxide synthase 2 0.364 0.923 4.0E-15
CUI: C0242488
Disease: Acute Lung Injury
Acute Lung Injury
disease 0.200 None 1.000 1 0 2006 2006
Entrez Id: 5074
Gene Symbol: PAWR
PAWR
pro-apoptotic WT1 regulator 0.542 0.846 9.0E-02
CUI: C0242488
Disease: Acute Lung Injury
Acute Lung Injury
disease 0.200 None 1.000 1 0 2007 2007
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
intercellular adhesion molecule 1 0.364 0.962 3.5E-02
CUI: C0242488
Disease: Acute Lung Injury
Acute Lung Injury
disease 0.500 None 1.000 1 0 2007 2016
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
plasminogen activator, urokinase 0.425 0.923 2.3E-06
CUI: C0242488
Disease: Acute Lung Injury
Acute Lung Injury
disease 0.210 None 1.000 2 0 2008 2013
Entrez Id: 7356
Gene Symbol: SCGB1A1
SCGB1A1
secretoglobin family 1A member 1 0.546 0.808 8.0E-04
CUI: C0242488
Disease: Acute Lung Injury
Acute Lung Injury
disease 0.200 None 1.000 1 0 2008 2008
Entrez Id: 5320
Gene Symbol: PLA2G2A
PLA2G2A
phospholipase A2 group IIA 0.488 0.808 9.7E-02
CUI: C0242488
Disease: Acute Lung Injury
Acute Lung Injury
disease 0.200 None 1.000 1 0 2009 2009
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
CUI: C0242488
Disease: Acute Lung Injury
Acute Lung Injury
disease 0.200 None 1.000 1 0 2009 2009
Entrez Id: 7056
Gene Symbol: THBD
THBD
thrombomodulin 0.457 0.769 5.4E-02
CUI: C0242488
Disease: Acute Lung Injury
Acute Lung Injury
disease 0.200 None 1.000 1 0 2009 2009
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
toll like receptor 4 0.321 0.962 4.6E-09
CUI: C0242488
Disease: Acute Lung Injury
Acute Lung Injury
disease 0.200 None 1.000 1 0 2009 2009