Source: ANIMAL_MODELS

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4160
Gene Symbol: MC4R
MC4R
melanocortin 4 receptor 0.535 0.692 9.2E-04
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.200 None 1.000 2 0 2005 2011
Entrez Id: 3638
Gene Symbol: INSIG1
INSIG1
insulin induced gene 1 0.695 0.500 1.3E-03
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.200 None 1.000 1 0 2004 2004
Entrez Id: 348
Gene Symbol: APOE
APOE
apolipoprotein E 0.338 0.962 1.9E-03
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.200 None 1.000 1 0 2018 2018
Entrez Id: 1401
Gene Symbol: CRP
CRP
C-reactive protein 0.299 0.962 3.7E-03
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.200 None 1.000 1 0 2011 2011
Entrez Id: 3586
Gene Symbol: IL10
IL10
interleukin 10 0.281 0.923 5.9E-03
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.200 None 1.000 1 0 2008 2008
Entrez Id: 57817
Gene Symbol: HAMP
HAMP
hepcidin antimicrobial peptide 0.433 0.846 8.2E-03
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.200 None 1.000 1 0 2008 2008
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
peroxisome proliferator activated receptor gamma 0.358 0.885 2.9E-02
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.210 None 1.000 1 0 2004 2010
Entrez Id: 5465
Gene Symbol: PPARA
PPARA
peroxisome proliferator activated receptor alpha 0.432 0.885 3.0E-02
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.530 None 1.000 1 0 2006 2018
Entrez Id: 3606
Gene Symbol: IL18
IL18
interleukin 18 0.365 0.923 3.1E-02
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.200 None 1.000 1 0 2008 2008
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
serpin family E member 1 0.359 0.885 4.4E-02
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.200 None 1.000 1 0 2014 2014
Entrez Id: 8517
Gene Symbol: IKBKG
IKBKG
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma 0.493 0.769 8.5E-02
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.200 None 0 0
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
sirtuin 1 0.378 0.885 8.7E-02
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.260 None 1.000 0 0 2012 2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
interleukin 1 beta 0.276 0.962 0.13
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.200 None 1.000 1 0 2007 2007
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
superoxide dismutase 2 0.379 0.923 0.15
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.200 None 1.000 1 0 2001 2001
Entrez Id: 7295
Gene Symbol: TXN
TXN
thioredoxin 0.447 0.885 0.20
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.200 None 1.000 1 0 2008 2008
Entrez Id: 10400
Gene Symbol: PEMT
PEMT
phosphatidylethanolamine N-methyltransferase 0.653 0.538 0.23
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.200 None 1.000 1 0 2007 2007
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
phosphatase and tensin homolog 0.305 0.923 0.26
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.200 None 1.000 1 0 2008 2008
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.248 0.962 0.32
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.210 None 1.000 1 0 2009 2009
Entrez Id: 3952
Gene Symbol: LEP
LEP
leptin 0.349 0.846 0.46
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.200 None 1.000 2 0 2011 2015
Entrez Id: 2645
Gene Symbol: GCK
GCK
glucokinase 0.523 0.808 0.63
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.200 None 1.000 1 0 2013 2013
Entrez Id: 4040
Gene Symbol: LRP6
LRP6
LDL receptor related protein 6 0.536 0.808 0.70
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.200 None 1.000 2 0 2014 2015
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
signal transducer and activator of transcription 4 0.471 0.769 0.77
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.200 None 1.000 1 0 2008 2008
Entrez Id: 3309
Gene Symbol: HSPA5
HSPA5
heat shock protein family A (Hsp70) member 5 0.434 0.885 0.77
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.200 None 1.000 1 0 2013 2013
Entrez Id: 5009
Gene Symbol: OTC
OTC
ornithine carbamoyltransferase 0.565 0.846 0.87
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.200 None 1.000 1 0 2009 2009
Entrez Id: 4976
Gene Symbol: OPA1
OPA1
OPA1 mitochondrial dynamin like GTPase 0.510 0.846 0.99
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.200 None 1.000 1 0 2014 2014