Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
epidermal growth factor receptor 0.295 0.885 0.37
Squamous cell carcinoma of the head and neck
disease 0.500 None 0.982 277 18 1992 2020
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
Squamous cell carcinoma of the head and neck
disease 0.500 None 0.973 219 86 1991 2020
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
cyclin dependent kinase inhibitor 2A 0.300 0.885 0.39
Squamous cell carcinoma of the head and neck
disease 0.500 None 0.983 115 9 1994 2019
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10
H3 histone pseudogene 10 0.350 0.846
Squamous cell carcinoma of the head and neck
disease 0.100 None 0.986 70 0 1995 2019
Entrez Id: 29126
Gene Symbol: CD274
CD274
CD274 molecule 0.324 0.923 1.9E-02
Squamous cell carcinoma of the head and neck
disease 0.100 None 1.000 70 0 2015 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.292 0.923 1.00
Squamous cell carcinoma of the head and neck
disease 0.500 None 1.000 68 29 2001 2020
Entrez Id: 595
Gene Symbol: CCND1
CCND1
cyclin D1 0.344 0.923 0.89
Squamous cell carcinoma of the head and neck
disease 0.400 None 1.000 52 1 1994 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
signal transducer and activator of transcription 3 0.320 0.923 1.00
Squamous cell carcinoma of the head and neck
disease 0.400 None 0.957 47 0 2000 2020
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta 0.322 0.885 1.00
Squamous cell carcinoma of the head and neck
disease 0.100 None 1.000 46 0 2001 2020
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta 0.319 0.885 1.00
Squamous cell carcinoma of the head and neck
disease 0.100 None 1.000 46 0 2001 2020
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma 0.320 0.885 1.4E-06
Squamous cell carcinoma of the head and neck
disease 0.100 None 1.000 46 0 2001 2020
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
vascular endothelial growth factor A 0.266 0.923 2.4E-05
Squamous cell carcinoma of the head and neck
disease 0.100 None 1.000 33 0 1999 2019
Entrez Id: 960
Gene Symbol: CD44
CD44
CD44 molecule (Indian blood group) 0.363 0.962 2.4E-07
Squamous cell carcinoma of the head and neck
disease 0.100 None 0.970 33 0 2001 2019
Entrez Id: 207
Gene Symbol: AKT1
AKT1
AKT serine/threonine kinase 1 0.311 0.962 0.98
Squamous cell carcinoma of the head and neck
disease 0.400 None 1.000 32 0 2005 2020
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
Squamous cell carcinoma of the head and neck
disease 0.400 None 0.966 29 3 1999 2019
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
single-strand-selective monofunctional uracil-DNA glycosylase 1 0.322 0.923 4.5E-04
Squamous cell carcinoma of the head and neck
disease 0.100 None 1.000 28 0 2017 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.248 0.962 0.32
Squamous cell carcinoma of the head and neck
disease 0.100 None 0.963 27 0 2001 2019
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
hypoxia inducible factor 1 subunit alpha 0.327 0.923 0.98
Squamous cell carcinoma of the head and neck
disease 0.100 None 1.000 26 2 2003 2020
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
erb-b2 receptor tyrosine kinase 2 0.328 0.923 6.0E-03
Squamous cell carcinoma of the head and neck
disease 0.200 None 0.958 24 2 1992 2019
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
glutathione S-transferase mu 1 0.380 0.923 2.1E-03
Squamous cell carcinoma of the head and neck
disease 0.100 None 0.957 23 0 1998 2015
Entrez Id: 8626
Gene Symbol: TP63
TP63
tumor protein p63 0.362 0.769 1.00
Squamous cell carcinoma of the head and neck
disease 0.100 None 1.000 22 0 2003 2019
Entrez Id: 1950
Gene Symbol: EGF
EGF
epidermal growth factor 0.357 0.923 8.5E-17
Squamous cell carcinoma of the head and neck
disease 0.100 None 1.000 21 0 2004 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
phosphatase and tensin homolog 0.305 0.923 0.26
Squamous cell carcinoma of the head and neck
disease 0.800 strong 0.952 21 3 1972 2019
Entrez Id: 596
Gene Symbol: BCL2
BCL2
BCL2 apoptosis regulator 0.291 0.885 0.56
Squamous cell carcinoma of the head and neck
disease 0.100 None 1.000 21 0 1997 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.231 0.962 0.80
Squamous cell carcinoma of the head and neck
disease 0.100 None 1.000 21 0 1995 2020