Source: CURATED

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.700 None 0.989 8 67 1991 2018
Entrez Id: 324
Gene Symbol: APC
APC
APC regulator of WNT signaling pathway 0.373 0.962 1.00
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.900 None 0.982 7 12 1990 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.400 None 1.000 6 0 1999 2019
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
toll like receptor 4 0.321 0.962 4.6E-09
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.340 None 1.000 2 0 2006 2011
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
colony stimulating factor 2 0.330 0.962 0.83
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.320 None 1.000 1 0 2004 2017
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
C-X-C motif chemokine ligand 8 0.310 0.962 2.7E-04
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.350 None 1.000 1 0 2003 2013
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
transforming growth factor beta 1 0.287 0.962 3.7E-02
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.400 None 1.000 1 1 1999 2014
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.231 0.962 0.80
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.390 None 1.000 1 0 2003 2017
Entrez Id: 207
Gene Symbol: AKT1
AKT1
AKT serine/threonine kinase 1 0.311 0.962 0.98
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.350 None 1.000 0 0 2004 2010
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
KRAS proto-oncogene, GTPase 0.320 0.923 7.9E-04
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.500 None 0.983 3 12 1990 2019
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
matrix metallopeptidase 2 0.333 0.923 0.84
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.700 None 1.000 2 1 1996 2016
Entrez Id: 59352
Gene Symbol: LGR6
LGR6
leucine rich repeat containing G protein-coupled receptor 6 0.502 0.923 2.9E-06
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.300 None 1.000 2 0 2008 2011
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
superoxide dismutase 2 0.379 0.923 0.15
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.310 None 1.000 2 0 2000 2003
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
toll like receptor 2 0.361 0.923 1.0E-06
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.320 None 1.000 2 0 2006 2010
Entrez Id: 142
Gene Symbol: PARP1
PARP1
poly(ADP-ribose) polymerase 1 0.389 0.923 3.3E-04
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.310 None 1.000 1 0 2016 2018
Entrez Id: 1544
Gene Symbol: CYP1A2
CYP1A2
cytochrome P450 family 1 subfamily A member 2 0.494 0.923 2.5E-10
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.320 None 1.000 1 0 2007 2011
Entrez Id: 2100
Gene Symbol: ESR2
ESR2
estrogen receptor 2 0.400 0.923 4.5E-08
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.340 None 1.000 1 0 2004 2014
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
glutathione S-transferase mu 1 0.380 0.923 2.1E-03
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.380 None 1.000 1 0 1996 2020
Entrez Id: 3439
Gene Symbol: IFNA1
IFNA1
interferon alpha 1 0.371 0.923
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.300 None 1.000 1 0 2004 2004
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
SMAD family member 3 0.415 0.923 0.80
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.400 None 1.000 1 1 2019 2019
Entrez Id: 4609
Gene Symbol: MYC
MYC
MYC proto-oncogene, bHLH transcription factor 0.344 0.923 1.00
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.390 None 1.000 1 0 1990 2019
Entrez Id: 811
Gene Symbol: CALR
CALR
calreticulin 0.413 0.923 0.89
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.300 None 1.000 1 0 2007 2007
Entrez Id: 841
Gene Symbol: CASP8
CASP8
caspase 8 0.404 0.923 3.7E-06
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.310 None 1.000 1 0 2003 2007
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.292 0.923 1.00
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.490 None 1.000 0 32 2004 2019
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
methylenetetrahydrofolate reductase 0.337 0.885 3.2E-10
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.400 None 1.000 8 0 2002 2014