| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
BCL2 apoptosis regulator | 0.291 | 0.885 | 0.56 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2019 | 2019 | ||||||||
|
KRAS proto-oncogene, GTPase | 0.320 | 0.923 | 7.9E-04 |
|
disease | 0.200 | None | 1.000 | 1 | 0 | 2014 | 2014 | ||||||||
|
actin beta | 0.325 | 0.923 | 0.99 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2001 | 2001 | ||||||||
|
proopiomelanocortin | 0.356 | 0.846 | 1.2E-04 |
|
disease | 0.100 | None | 1.000 | 21 | 4 | 1994 | 2019 | ||||||||
|
growth hormone 1 | 0.373 | 0.923 | 3.0E-02 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2004 | 2004 | ||||||||
|
protein tyrosine phosphatase non-receptor type 11 | 0.385 | 0.923 | 1.00 |
|
disease | 0.200 | None | 1.000 | 1 | 0 | 2004 | 2004 | ||||||||
|
Raf-1 proto-oncogene, serine/threonine kinase | 0.418 | 0.885 | 0.85 |
|
disease | 0.200 | None | 1.000 | 2 | 0 | 2011 | 2012 | ||||||||
|
2,4-dienoyl-CoA reductase 1 | 0.426 | 0.885 | 4.5E-14 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2017 | 2017 | ||||||||
|
GLI family zinc finger 3 | 0.436 | 0.846 | 1.00 |
|
disease | 0.020 | None | 0.500 | 2 | 0 | 1991 | 1997 | ||||||||
|
cyclin dependent kinase inhibitor 1C | 0.456 | 0.846 | 0.82 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2014 | 2014 | ||||||||
|
ATR serine/threonine kinase | 0.456 | 0.923 | 3.5E-09 |
|
disease | 0.200 | None | 0 | 0 | |||||||||||
|
cell division cycle 42 | 0.458 | 0.846 | 0.79 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2001 | 2001 | ||||||||
|
SOS Ras/Rac guanine nucleotide exchange factor 1 | 0.485 | 0.808 | 1.00 |
|
disease | 0.230 | None | 1.000 | 4 | 0 | 2000 | 2017 | ||||||||
|
Rho/Rac guanine nucleotide exchange factor 2 | 0.502 | 0.769 | 1.00 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2000 | 2010 | ||||||||
|
steroidogenic acute regulatory protein | 0.513 | 0.808 | 8.8E-11 |
|
disease | 0.060 | None | 0.833 | 6 | 3 | 2009 | 2019 | ||||||||
|
melanocortin 1 receptor | 0.524 | 0.808 | 8.1E-11 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2012 | 2012 | ||||||||
|
Ras like without CAAX 1 | 0.527 | 0.808 | 0.13 |
|
disease | 0.200 | None | 1.000 | 1 | 0 | 2019 | 2019 | ||||||||
|
Ras protein specific guanine nucleotide releasing factor 1 | 0.537 | 0.769 | 1.00 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2000 | 2017 | ||||||||
|
centromere protein J | 0.546 | 0.846 | 2.1E-27 |
|
disease | 0.200 | None | 0 | 0 | |||||||||||
|
cytochrome P450 family 11 subfamily A member 1 | 0.547 | 0.731 | 5.5E-07 |
|
disease | 0.020 | None | 0.500 | 2 | 0 | 2015 | 2019 | ||||||||
|
leucine zipper like transcription regulator 1 | 0.547 | 0.808 | 1.0E-92 |
|
disease | 0.200 | None | 1.000 | 1 | 0 | 2018 | 2018 | ||||||||
|
thioredoxin reductase 2 | 0.548 | 0.731 | 3.5E-11 |
|
disease | 0.040 | None | 0.750 | 4 | 0 | 2014 | 2019 | ||||||||
|
SPARC related modular calcium binding 1 | 0.565 | 0.846 | 9.5E-03 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 1994 | 1994 | ||||||||
|
FYVE, RhoGEF and PH domain containing 1 | 0.573 | 0.731 | 1.00 |
|
disease | 0.800 | definitive | 0.935 | 31 | 12 | 1994 | 2017 | ||||||||
|
melanocortin 2 receptor | 0.582 | 0.654 | 3.1E-04 |
|
disease | 0.100 | None | 0.935 | 31 | 4 | 1994 | 2019 |