×
Entrez Id:
3953
Gene Symbol:
LEPR
LEPR
Obesity
0.700
Biomarker
MGD
Adipocyte Xbp1s overexpression drives uridine production and reduces obesity.
29551634
2018
×
Entrez Id:
3953
Gene Symbol:
LEPR
LEPR
Obesity
0.700
Biomarker
RGD
Early development of podocyte injury independently of hyperglycemia and elevations in arterial pressure in nondiabetic obese Dahl SS leptin receptor mutant rats.
27465994
2016
×
Entrez Id:
3953
Gene Symbol:
LEPR
LEPR
Obesity
0.700
Biomarker
MGD
SHBG-C57BL/ksJ-db/db: A New Mouse Model to Study SHBG Expression and Regulation During Obesity Development.
26441241
2015
×
Entrez Id:
3953
Gene Symbol:
LEPR
LEPR
Obesity
0.700
Biomarker
MGD
Type 2 diabetes and congenital hyperinsulinism cause DNA double-strand breaks and p53 activity in β cells.
24332968
2014
×
Entrez Id:
3953
Gene Symbol:
LEPR
LEPR
Obesity
0.700
Biomarker
MGD
Prostaglandin transporter modulates wound healing in diabetes by regulating prostaglandin-induced angiogenesis.
22609345
2012
×
Entrez Id:
3953
Gene Symbol:
LEPR
LEPR
Obesity
0.700
Biomarker
RGD
Endogenous leptin receptor signaling in the medial nucleus tractus solitarius affects meal size and potentiates intestinal satiation signals.
22693203
2012
×
Entrez Id:
3953
Gene Symbol:
LEPR
LEPR
Obesity
0.700
Biomarker
MGD
Tyrosine-dependent and -independent actions of leptin receptor in control of energy balance and glucose homeostasis.
19015522
2008
×
Entrez Id:
3953
Gene Symbol:
LEPR
LEPR
Obesity
0.700
Biomarker
MGD
Leptin regulates neointima formation after arterial injury through mechanisms independent of blood pressure and the leptin receptor/STAT3 signaling pathways involved in energy balance.
17095713
2007
×
Entrez Id:
3953
Gene Symbol:
LEPR
LEPR
Obesity
0.700
Biomarker
MGD
Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions.
17268472
2007
×
Entrez Id:
3953
Gene Symbol:
LEPR
LEPR
Obesity
0.700
Biomarker
MGD
The long form of leptin receptor (Ob-R(b) ) is required for satiety; mice lacking this receptor (db/db mice) are also substantially obese .
16373670
2006
×
Entrez Id:
3953
Gene Symbol:
LEPR
LEPR
Obesity
0.700
Biomarker
MGD
Leptin increases axonal growth cone size in developing mouse cortical neurons by convergent signals inactivating glycogen synthase kinase-3beta.
16522636
2006
×
Entrez Id:
3953
Gene Symbol:
LEPR
LEPR
Obesity
0.700
Biomarker
MGD
Myocardial infarction and heart failure in the db/db diabetic mouse.
16113078
2006
×
Entrez Id:
3953
Gene Symbol:
LEPR
LEPR
Obesity
0.700
Biomarker
MGD
Endothelial nitric oxide synthase deficiency produces accelerated nephropathy in diabetic mice.
16971655
2006
×
Entrez Id:
3953
Gene Symbol:
LEPR
LEPR
Obesity
0.700
Biomarker
MGD
Increased myocardial oxygen consumption reduces cardiac efficiency in diabetic mice.
16443782
2006
×
Entrez Id:
3953
Gene Symbol:
LEPR
LEPR
Obesity
0.700
Biomarker
MGD
Severe pulmonary metastasis in obese and diabetic mice.
16998795
2006
×
Entrez Id:
3953
Gene Symbol:
LEPR
LEPR
Obesity
0.700
Biomarker
MGD
Deletion of Cdkn1b ameliorates hyperglycemia by maintaining compensatory hyperinsulinemia in diabetic mice.
15685168
2005
×
Entrez Id:
3953
Gene Symbol:
LEPR
LEPR
Obesity
0.700
Biomarker
MGD
The RAGE axis in early diabetic retinopathy.
16043866
2005
×
Entrez Id:
3953
Gene Symbol:
LEPR
LEPR
Obesity
0.700
Biomarker
MGD
COX-2 up-regulation and vascular smooth muscle contractile hyperreactivity in spontaneous diabetic db/db mice.
15885672
2005
×
Entrez Id:
3953
Gene Symbol:
LEPR
LEPR
Obesity
0.700
Biomarker
MGD
Disruption of neural signal transducer and activator of transcription 3 causes obesity, diabetes, infertility, and thermal dysregulation.
15070774
2004
×
Entrez Id:
3953
Gene Symbol:
LEPR
LEPR
Obesity
0.700
Biomarker
MGD
Leptin receptor signaling in POMC neurons is required for normal body weight homeostasis.
15207242
2004
×
Entrez Id:
3953
Gene Symbol:
LEPR
LEPR
Obesity
0.700
Biomarker
MGD
Night-time restricted feeding normalises clock genes and Pai-1 gene expression in the db/db mouse liver.
15309293
2004
×
Entrez Id:
3953
Gene Symbol:
LEPR
LEPR
Obesity
0.700
Biomarker
MGD
Lepr(db/db) mice are obese due to a defect in the signaling portion of the leptin receptor , which has led to extensive study of this highly conserved system over the past several years.
15389315
2004
×
Entrez Id:
3953
Gene Symbol:
LEPR
LEPR
Obesity
0.700
Biomarker
MGD
RAGE drives the development of glomerulosclerosis and implicates podocyte activation in the pathogenesis of diabetic nephropathy.
12651605
2003
×
Entrez Id:
3953
Gene Symbol:
LEPR
LEPR
Obesity
0.700
Biomarker
MGD
Age-dependent changes in metabolism, contractile function, and ischemic sensitivity in hearts from db/db mice.
12540618
2003
×
Entrez Id:
3953
Gene Symbol:
LEPR
LEPR
Obesity
0.700
Biomarker
MGD
STAT3 signalling is required for leptin regulation of energy balance but not reproduction.
12594516
2003