| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
AKT serine/threonine kinase 1 | 0.311 | 0.962 | 0.98 |
|
disease | 0.600 | limited | 0.984 | 122 | 1 | 2002 | 2020 | ||||||||
|
checkpoint kinase 2 | 0.460 | 0.808 | 1.2E-24 |
|
disease | 0.700 | limited | 0.885 | 26 | 4 | 2003 | 2019 | ||||||||
|
mutL homolog 1 | 0.399 | 0.808 | 3.4E-05 |
|
disease | 0.800 | strong | 0.973 | 478 | 17 | 1993 | 2020 | ||||||||
|
APC regulator of WNT signaling pathway | 0.373 | 0.962 | 1.00 |
|
disease | 0.800 | strong | 0.972 | 353 | 20 | 1990 | 2020 | ||||||||
|
mutS homolog 2 | 0.406 | 0.808 | 0.90 |
|
disease | 0.800 | strong | 0.971 | 277 | 7 | 1993 | 2020 | ||||||||
|
mutY DNA glycosylase | 0.521 | 0.769 | 1.3E-18 |
|
disease | 0.500 | strong | 0.947 | 117 | 13 | 2002 | 2019 | ||||||||
|
mutS homolog 6 | 0.462 | 0.731 | 3.7E-05 |
|
disease | 0.600 | strong | 0.974 | 107 | 5 | 1988 | 2020 | ||||||||
|
SMAD family member 4 | 0.401 | 0.808 | 1.00 |
|
disease | 0.700 | strong | 0.981 | 102 | 0 | 1996 | 2020 | ||||||||
|
phosphatase and tensin homolog | 0.305 | 0.923 | 0.26 |
|
disease | 0.400 | strong | 0.964 | 83 | 4 | 2000 | 2019 | ||||||||
|
PMS1 homolog 2, mismatch repair system component | 0.484 | 0.808 | 4.5E-27 |
|
disease | 0.500 | strong | 0.967 | 60 | 5 | 1998 | 2020 | ||||||||
|
NRAS proto-oncogene, GTPase | 0.390 | 0.808 | 0.49 |
|
disease | 0.800 | strong | 0.966 | 59 | 5 | 1993 | 2020 | ||||||||
|
DNA polymerase epsilon, catalytic subunit | 0.526 | 0.731 | 8.0E-27 |
|
disease | 0.600 | strong | 1.000 | 27 | 5 | 2013 | 2020 | ||||||||
|
DNA polymerase delta 1, catalytic subunit | 0.507 | 0.769 | 2.4E-06 |
|
disease | 0.600 | strong | 0.944 | 17 | 3 | 1995 | 2020 | ||||||||
|
serine/threonine kinase 11 | 0.435 | 0.808 | 0.99 |
|
disease | 0.600 | strong | 1.000 | 14 | 0 | 1998 | 2019 | ||||||||
|
nth like DNA glycosylase 1 | 0.623 | 0.615 | 5.7E-10 |
|
disease | 0.390 | strong | 1.000 | 9 | 1 | 2006 | 2019 | ||||||||
|
bone morphogenetic protein receptor type 1A | 0.522 | 0.731 | 0.90 |
|
disease | 0.340 | strong | 1.000 | 4 | 0 | 2015 | 2018 | ||||||||
|
KRAS proto-oncogene, GTPase | 0.320 | 0.923 | 7.9E-04 |
|
disease | 0.600 | None | 0.963 | 1005 | 11 | 1990 | 2020 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.700 | None | 0.947 | 659 | 14 | 1989 | 2020 | ||||||||
|
B-Raf proto-oncogene, serine/threonine kinase | 0.319 | 0.846 | 1.00 |
|
disease | 0.700 | None | 0.976 | 617 | 6 | 2002 | 2020 | ||||||||
|
epidermal growth factor receptor | 0.295 | 0.885 | 0.37 |
|
disease | 0.400 | None | 0.991 | 568 | 12 | 1992 | 2020 | ||||||||
|
catenin beta 1 | 0.303 | 0.885 | 1.00 |
|
disease | 0.700 | None | 0.983 | 464 | 5 | 1997 | 2020 | ||||||||
|
CEA cell adhesion molecule 5 | 0.420 | 0.846 | 4.2E-10 |
|
disease | 0.100 | None | 0.990 | 288 | 0 | 1986 | 2020 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
disease | 0.700 | None | 0.985 | 266 | 3 | 2002 | 2020 | ||||||||
|
mannose receptor C-type 1 | 0.413 | 0.846 | 0.94 |
|
disease | 0.100 | None | 0.951 | 247 | 1 | 1995 | 2020 | ||||||||
|
prostaglandin-endoperoxide synthase 2 | 0.314 | 0.962 | 1.00 |
|
disease | 0.400 | None | 0.979 | 237 | 11 | 1994 | 2020 |