Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD Diabetic rat testes: morphological and functional alterations. 19891634

2009

Entrez Id: 623
Gene Symbol: BDKRB1
BDKRB1
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD Regulation of cardiac bradykinin B1- and B2-receptor mRNA in experimental ischemic, diabetic, and pressure-overload-induced cardiomyopathy. 12489796

2002

Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD Low-dose treatment with atorvastatin leads to anti-oxidative and anti-inflammatory effects in diabetes mellitus. 17669395

2007

Entrez Id: 623
Gene Symbol: BDKRB1
BDKRB1
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD Up-regulation of kinin B1 receptor in the lung of streptozotocin-diabetic rat: autoradiographic and functional evidence. 12522068

2003

Entrez Id: 3667
Gene Symbol: IRS1
IRS1
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Therapeutic RGD Effects of selenium and exendin-4 on glucagon-like peptide-1 receptor, IRS-1, and Raf-1 in the liver of diabetic rats. 22983684

2012

Entrez Id: 3643
Gene Symbol: INSR
INSR
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD Reduced expression of insulin receptors in the kidneys of insulin-resistant rats. 17855644

2007

Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD Protective effects of cyclooxygenase-2 gene inactivation against peripheral nerve dysfunction and intraepidermal nerve fiber loss in experimental diabetes. 17720896

2007

Entrez Id: 6514
Gene Symbol: SLC2A2
SLC2A2
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD SLC2A2 gene expression in kidney of diabetic rats is regulated by HNF-1alpha and HNF-3beta. 19433262

2009

Entrez Id: 3643
Gene Symbol: INSR
INSR
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 ModifyingMutation RGD Effects of STZ-induced diabetes and fasting on insulin receptor mRNA expression and insulin receptor gene transcription in rat liver. 1280238

1992

Entrez Id: 3643
Gene Symbol: INSR
INSR
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD Genomic actions of 1,25-dihydroxyvitamin D3 on insulin receptor gene expression, insulin receptor number and insulin activity in the kidney, liver and adipose tissue of streptozotocin-induced diabetic rats. 18638371

2008

Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD The timing of re-institution of good blood glucose control affects apoptosis and expression of Bax and Bcl-2 in the retina of diabetic rats. 18991018

2009

Entrez Id: 3479
Gene Symbol: IGF1
IGF1
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD Differentially expressed angiogenic genes in diabetic erectile tissue - results from a microarray screening. 22133301

2012

Entrez Id: 488
Gene Symbol: ATP2A2
ATP2A2
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD Early energy metabolism-related molecular events in skeletal muscle of diabetic rats: The effects of l-arginine and SOD mimic. 28483572

2017

Entrez Id: 3667
Gene Symbol: IRS1
IRS1
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD Altered gene expression involved in insulin signaling pathway in type II diabetic osteoporosis rats model. 22820932

2013

Entrez Id: 4843
Gene Symbol: NOS2
NOS2
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD The neuroprotective effect of agmatine after focal cerebral ischemia in diabetic rats. 21993016

2012

Entrez Id: 2876
Gene Symbol: GPX1
GPX1
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD Gene expressions of Mn-SOD and GPx-1 in streptozotocin-induced diabetes: effect of antioxidants. 19229592

2009

Entrez Id: 3458
Gene Symbol: IFNG
IFNG
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD IL-2 and IFN-gamma in the retina of diabetic rats. 20213480

2010

Entrez Id: 598
Gene Symbol: BCL2L1
BCL2L1
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD Streptozotocin-induced diabetes increases the interaction of Bad/Bcl-XL and decreases the binding of pBad/14-3-3 in rat testis. 17870134

2007

Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD Type 1 diabetes-induced hyper-responsiveness to 5-hydroxytryptamine in rat pulmonary arteries via oxidative stress and induction of cyclooxygenase-2. 21521772

2011

Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD Curcumin supplementation lowers TNF-alpha, IL-6, IL-8, and MCP-1 secretion in high glucose-treated cultured monocytes and blood levels of TNF-alpha, IL-6, MCP-1, glucose, and glycosylated hemoglobin in diabetic rats. 18976114

2009

Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD Regulation of IRS-2 signaling by IGF-1 receptor in the diabetic rat heart. 20555424

2010

Entrez Id: 6376
Gene Symbol: CX3CL1
CX3CL1
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD Fractalkine and its receptor, CX3CR1, upregulation in streptozotocin-induced diabetic kidneys. 15153757

2004

Entrez Id: 3643
Gene Symbol: INSR
INSR
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD Effect of tetrahydrocurcumin on insulin receptor status in type 2 diabetic rats: studies on insulin binding to erythrocytes. 18376071

2008

Entrez Id: 4353
Gene Symbol: MPO
MPO
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD The effect of experimental diabetes on the circadian pattern of adenosine deaminase and myeloperoxidase activities in rat liver. 18436980

2008

Entrez Id: 3643
Gene Symbol: INSR
INSR
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD Impaired insulin action but normal insulin receptor activity in diabetic rat liver: effect of vanadate. 2180315

1990