×
Entrez Id: 9638
Gene Symbol: FEZ1
FEZ1
Parkinson Disease
0.200
Biomarker
RGD
Immunohistochemistry was performed to identify the cellular localization of FEZ1 in sham-lesioned and PD rats.
23888906 2014
×
Entrez Id: 1627
Gene Symbol: DBN1
DBN1
Parkinson Disease
0.200
Therapeutic
RGD
Immunoelectron microscopic examinations confirmed that drebrin -immunoreactive spines became enlarged in the dopamine-denervated striatum of the levodopa-induced dyskinesia model, but not in the Parkinson's disease model.
23241013 2013
×
Entrez Id: 57165
Gene Symbol: GJC2
GJC2
Parkinson Disease
0.200
Therapeutic
RGD
Nigrostriatal proteomics of cypermethrin-induced dopaminergic neurodegeneration: microglial activation-dependent and -independent regulations.
21561882 2011
×
Entrez Id: 10094
Gene Symbol: ARPC3
ARPC3
Parkinson Disease
0.200
Therapeutic
RGD
Antiparkinsonian trophic action of glial cell line-derived neurotrophic factor and transforming growth factor β1 is enhanced after co-infusion in rats.
20713051 2010
×
Entrez Id: 1490
Gene Symbol: CCN2
CCN2
Parkinson Disease
0.200
Biomarker
RGD
Increased MMP-3 and CTGF expression during lipopolysaccharide-induced dopaminergic neurodegeneration.
19463894 2009
×
Entrez Id: 57657
Gene Symbol: HCN3
HCN3
Parkinson Disease
0.200
Biomarker
RGD
Our cell-type selective transcriptome analyses of BGON in the rat 6-hydroxydopamine (6-OHDA) model of PD identified the ion channel HCN3 as a likely contributor to altered neuronal excitability.
19320057 2009
×
Entrez Id: 157
Gene Symbol: GRK3
GRK3
Parkinson Disease
0.200
Biomarker
RGD
Altered expression and subcellular distribution of GRK subtypes in the dopamine-depleted rat basal ganglia is not normalized by l-DOPA treatment.
17996024 2008
×
Entrez Id: 156
Gene Symbol: GRK2
GRK2
Parkinson Disease
0.200
Biomarker
RGD
Altered expression and subcellular distribution of GRK subtypes in the dopamine-depleted rat basal ganglia is not normalized by l-DOPA treatment.
17996024 2008
×
Entrez Id: 356
Gene Symbol: FASLG
FASLG
Parkinson Disease
0.200
Biomarker
RGD
Expression of FasL and its interaction with Fas are mediated by c-Jun N-terminal kinase (JNK) pathway in 6-OHDA-induced rat model of Parkinson disease.
17959308 2007
×
Entrez Id: 1739
Gene Symbol: DLG1
DLG1
Parkinson Disease
0.200
Biomarker
RGD
Here, we show that expression and subcellular distribution of PSD-95 and SAP97 are altered in the striatum of unilateral 6-OHDA-lesioned rats following repeated vehicle (a model of PD ) or L-DOPA administration (a model of L-DOPA-induced dyskinesia).
15703272 2005
×
Entrez Id: 111
Gene Symbol: ADCY5
ADCY5
Parkinson Disease
0.200
Biomarker
MGD
Motor dysfunction in type 5 adenylyl cyclase-null mice.
12665504 2003
×
Entrez Id: 54700
Gene Symbol: RRN3
RRN3
Parkinson Disease
0.200
Biomarker
MGD
×
Entrez Id: 1352
Gene Symbol: COX10
COX10
Parkinson Disease
0.200
Biomarker
MGD
×
Entrez Id: 3297
Gene Symbol: HSF1
HSF1
Parkinson Disease
0.210
Therapeutic
RGD
Modulatory effects of sodium salicylate on the factors affecting protein aggregation during rotenone induced Parkinson's disease pathology.
24852355 2014
×
Entrez Id: 3297
Gene Symbol: HSF1
HSF1
Parkinson Disease
0.210
Biomarker
RGD
Long-term heat shock proteins (HSPs) induction by carbenoxolone improves hallmark features of Parkinson's disease in a rotenone-based model.
24296154 2014
×
Entrez Id: 3329
Gene Symbol: HSPD1
HSPD1
Parkinson Disease
0.210
Biomarker
RGD
Taken together, our results suggested that Hsp60 could be released extracellularly to activate microglia in Parkinson's disease model.
23943523 2013
×
Entrez Id: 4537
Gene Symbol: ND3
ND3
Parkinson Disease
0.210
Biomarker
RGD
Protective effect of lycopene on oxidative stress and cognitive decline in rotenone induced model of Parkinson's disease.
21484267 2011
×
Entrez Id: 5764
Gene Symbol: PTN
PTN
Parkinson Disease
0.210
Therapeutic
RGD
Heparin-binding determinants of GDNF reduce its tissue distribution but are beneficial for the protection of nigral dopaminergic neurons.
19615368 2009
×
Entrez Id: 2870
Gene Symbol: GRK6
GRK6
Parkinson Disease
0.210
Biomarker
RGD
Altered expression and subcellular distribution of GRK subtypes in the dopamine-depleted rat basal ganglia is not normalized by l-DOPA treatment.
17996024 2008
×
Entrez Id: 3952
Gene Symbol: LEP
LEP
Parkinson Disease
0.210
Therapeutic
RGD
Leptin protects against 6-hydroxydopamine-induced dopaminergic cell death via mitogen-activated protein kinase signaling.
17895242 2007
×
Entrez Id: 25
Gene Symbol: ABL1
ABL1
Parkinson Disease
0.220
Biomarker
RGD
However, only c-Abl protein levels were found to be upregulated in PD brains.
24412932 2014
×
Entrez Id: 131
Gene Symbol: ADH7
ADH7
Parkinson Disease
0.220
Biomarker
MGD
Modeling Parkinson's disease genetics: altered function of the dopamine system in Adh4 knockout mice.
21075145 2011
×
Entrez Id: 84687
Gene Symbol: PPP1R9B
PPP1R9B
Parkinson Disease
0.220
Biomarker
RGD
Association of protein phosphatase 1 gamma 1 with spinophilin suppresses phosphatase activity in a Parkinson disease model.
18372251 2008
×
Entrez Id: 1742
Gene Symbol: DLG4
DLG4
Parkinson Disease
0.220
Biomarker
RGD
Here, we show that expression and subcellular distribution of PSD-95 and SAP97 are altered in the striatum of unilateral 6-OHDA-lesioned rats following repeated vehicle (a model of PD ) or L-DOPA administration (a model of L-DOPA-induced dyskinesia).
15703272 2005
×
Entrez Id: 8200
Gene Symbol: GDF5
GDF5
Parkinson Disease
0.230
Biomarker
RGD
It found that endogenous GDF5 , GDNF and their receptors are differentially expressed in two 6-hydroxydopamine lesion models of PD .
24373993 2014