| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
BRCA1 DNA repair associated | 0.367 | 0.923 | 9.2E-29 |
|
disease | 0.700 | None | 0.955 | 2682 | 104 | 1992 | 2020 | ||||||||
|
RAD51 paralog B | 0.556 | 0.769 | 2.1E-15 |
|
disease | 0.500 | None | 0.913 | 23 | 64 | 2009 | 2019 | ||||||||
|
BRCA2 DNA repair associated | 0.379 | 0.846 | 2.4E-25 |
|
disease | 0.700 | None | 0.950 | 1468 | 54 | 1994 | 2020 | ||||||||
|
estrogen receptor 1 | 0.324 | 0.962 | 1.00 |
|
disease | 0.700 | None | 0.968 | 2998 | 43 | 1981 | 2020 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.900 | None | 0.971 | 1183 | 43 | 1982 | 2020 | ||||||||
|
ATM serine/threonine kinase | 0.374 | 0.885 | 5.6E-47 |
|
disease | 0.500 | None | 0.934 | 229 | 30 | 1996 | 2020 | ||||||||
|
erb-b2 receptor tyrosine kinase 2 | 0.328 | 0.923 | 6.0E-03 |
|
disease | 0.600 | None | 0.972 | 4122 | 24 | 1987 | 2020 | ||||||||
|
checkpoint kinase 2 | 0.460 | 0.808 | 1.2E-24 |
|
disease | 0.700 | None | 0.952 | 165 | 23 | 2001 | 2019 | ||||||||
|
partner and localizer of BRCA2 | 0.485 | 0.769 | 3.0E-19 |
|
disease | 0.700 | None | 0.961 | 152 | 21 | 2007 | 2020 | ||||||||
|
fibroblast growth factor receptor 2 | 0.380 | 0.808 | 1.00 |
|
disease | 0.500 | None | 0.943 | 141 | 21 | 1996 | 2020 | ||||||||
|
progesterone receptor | 0.426 | 0.885 | 5.1E-02 |
|
disease | 0.400 | None | 0.936 | 581 | 18 | 1985 | 2020 | ||||||||
|
cytochrome P450 family 19 subfamily A member 1 | 0.410 | 0.885 | 1.7E-05 |
|
disease | 0.400 | None | 0.978 | 650 | 16 | 1993 | 2020 | ||||||||
|
cytochrome P450 family 24 subfamily A member 1 | 0.518 | 0.692 | 3.2E-23 |
|
disease | 0.400 | None | 0.857 | 21 | 14 | 2001 | 2020 | ||||||||
|
epidermal growth factor receptor | 0.295 | 0.885 | 0.37 |
|
disease | 0.400 | None | 0.974 | 570 | 13 | 1987 | 2020 | ||||||||
|
telomerase reverse transcriptase | 0.374 | 0.846 | 0.99 |
|
disease | 0.400 | None | 0.952 | 42 | 13 | 2000 | 2019 | ||||||||
|
transcription factor 7 like 2 | 0.485 | 0.846 | 1.00 |
|
disease | 0.200 | None | 1.000 | 19 | 13 | 2008 | 2019 | ||||||||
|
PGR antisense RNA 1 | 0.514 | 0.808 |
|
disease | 0.040 | None | 0.750 | 4 | 13 | 2002 | 2015 | |||||||||
|
ERCC excision repair 5, endonuclease | 0.499 | 0.731 | 2.7E-13 |
|
disease | 0.100 | None | 0.846 | 13 | 12 | 2003 | 2018 | ||||||||
|
BIVM-ERCC5 readthrough | 0.736 | 0.308 | 1.3E-15 |
|
disease | 0.010 | None | 1.000 | 1 | 12 | 2019 | 2019 | ||||||||
|
nibrin | 0.467 | 0.808 | 2.2E-16 |
|
disease | 0.200 | None | 0.891 | 46 | 11 | 2002 | 2019 | ||||||||
|
ERCC excision repair 2, TFIIH core complex helicase subunit | 0.420 | 0.846 | 7.1E-20 |
|
disease | 0.100 | None | 0.897 | 39 | 11 | 1995 | 2019 | ||||||||
|
mutL homolog 1 | 0.399 | 0.808 | 3.4E-05 |
|
disease | 0.200 | None | 0.943 | 35 | 11 | 2000 | 2020 | ||||||||
|
chromosome 11 open reading frame 65 | 0.670 | 0.462 | 2.0E-14 |
|
disease | 0.100 | None | 0 | 11 | |||||||||||
|
methylenetetrahydrofolate reductase | 0.337 | 0.885 | 3.2E-10 |
|
disease | 0.400 | None | 0.890 | 100 | 10 | 2002 | 2020 | ||||||||
|
catechol-O-methyltransferase | 0.400 | 0.923 | 1.1E-06 |
|
disease | 0.400 | None | 0.825 | 80 | 10 | 1997 | 2019 |