Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 26047
Gene Symbol: CNTNAP2
CNTNAP2
CUI: C0270824
Disease: Visual seizure
Visual seizure
0.200 Biomarker RGD Cntnap2 Knockout Rats and Mice Exhibit Epileptiform Activity and Abnormal Sleep-Wake Physiology. 28364455

2017

Entrez Id: 1476
Gene Symbol: CSTB
CSTB
CUI: C0270824
Disease: Visual seizure
Visual seizure
0.200 Biomarker RGD Seizures induce widespread upregulation of cystatin B, the gene mutated in progressive myoclonus epilepsy, in rat forebrain neurons. 10792446

2000

Entrez Id: 4519
Gene Symbol: CYTB
CYTB
CUI: C0270824
Disease: Visual seizure
Visual seizure
0.200 Biomarker RGD Structural and functional alterations in mitochondrial membrane in picrotoxin-induced epileptic rat brain. 15698621

2005

Entrez Id: 1641
Gene Symbol: DCX
DCX
CUI: C0270824
Disease: Visual seizure
Visual seizure
0.200 ModifyingMutation RGD Spontaneous epileptic manifestations in a DCX knockdown model of human double cortex. 20164125

2010

Entrez Id: 22943
Gene Symbol: DKK1
DKK1
CUI: C0270824
Disease: Visual seizure
Visual seizure
0.200 Biomarker RGD Induction of the Wnt inhibitor, Dickkopf-1, is associated with neurodegeneration related to temporal lobe epilepsy. 17437412

2007

Entrez Id: 1814
Gene Symbol: DRD3
DRD3
CUI: C0270824
Disease: Visual seizure
Visual seizure
0.500 Biomarker RGD Up-regulation of D3 dopaminergic receptor mRNA in the core of the nucleus accumbens accompanies the development of seizures in a genetic model of absence-epilepsy in the rat. 11597777

2001

Entrez Id: 1843
Gene Symbol: DUSP1
DUSP1
CUI: C0270824
Disease: Visual seizure
Visual seizure
0.200 Biomarker RGD MKP-3, a novel cytosolic protein-tyrosine phosphatase that exemplifies a new class of mitogen-activated protein kinase phosphatase. 8626780

1996

Entrez Id: 1843
Gene Symbol: DUSP1
DUSP1
CUI: C0270824
Disease: Visual seizure
Visual seizure
0.200 Biomarker RGD Transient expression of the mitogen-activated protein kinase phosphatase MKP-1 (3CH134/ERP1) in the rat brain after limbic epilepsy. 8883936

1996

Entrez Id: 1848
Gene Symbol: DUSP6
DUSP6
CUI: C0270824
Disease: Visual seizure
Visual seizure
0.200 Biomarker RGD Electroconvulsive seizures increase the expression of MAP kinase phosphatases in limbic regions of rat brain. 15496935

2005

Entrez Id: 1848
Gene Symbol: DUSP6
DUSP6
CUI: C0270824
Disease: Visual seizure
Visual seizure
0.200 Biomarker RGD MKP-3, a novel cytosolic protein-tyrosine phosphatase that exemplifies a new class of mitogen-activated protein kinase phosphatase. 8626780

1996

Entrez Id: 1958
Gene Symbol: EGR1
EGR1
CUI: C0270824
Disease: Visual seizure
Visual seizure
0.200 Biomarker RGD Changes in the Egr1 and Arc expression in brain structures of pentylenetetrazole-kindled rats. 23744421

2013

Entrez Id: 2021
Gene Symbol: ENDOG
ENDOG
CUI: C0270824
Disease: Visual seizure
Visual seizure
0.200 Biomarker RGD Nuclear translocation of mitochondrial cytochrome c, lysosomal cathepsins B and D, and three other death-promoting proteins within the first 60 minutes of generalized seizures. 20077427

2010

Entrez Id: 2026
Gene Symbol: ENO2
ENO2
CUI: C0270824
Disease: Visual seizure
Visual seizure
0.200 Biomarker RGD Biochemical brain markers and purinergic parameters in rat CSF after seizure induced by pentylenetetrazol. 15464860

2004

Entrez Id: 2056
Gene Symbol: EPO
EPO
CUI: C0270824
Disease: Visual seizure
Visual seizure
0.200 Therapeutic RGD The PI3K/Akt and ERK1/2 signaling pathways mediate the erythropoietin-modulated calcium influx in kainic acid-induced epilepsy. 23518641

2013

Entrez Id: 2066
Gene Symbol: ERBB4
ERBB4
CUI: C0270824
Disease: Visual seizure
Visual seizure
0.200 Biomarker RGD Neuregulin 1 represses limbic epileptogenesis through ErbB4 in parvalbumin-expressing interneurons. 22158510

2011

Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0270824
Disease: Visual seizure
Visual seizure
0.200 Biomarker RGD Increased expression of Fas (CD95/APO-1) in adult rat brain after kainate-induced seizures. 11435933

2001

Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C0270824
Disease: Visual seizure
Visual seizure
0.200 Biomarker RGD Seizure-associated induction of basic fibroblast growth factor and its receptor in the rat brain. 8072686

1994

Entrez Id: 8061
Gene Symbol: FOSL1
FOSL1
CUI: C0270824
Disease: Visual seizure
Visual seizure
0.200 Biomarker RGD Carbetapentane attenuates kainate-induced seizures via sigma-1 receptor modulation. 11488404

2001

Entrez Id: 2550
Gene Symbol: GABBR1
GABBR1
CUI: C0270824
Disease: Visual seizure
Visual seizure
0.200 Biomarker RGD GABA-B receptor activation in the rat globus pallidus potently suppresses pentylenetetrazol-induced tonic seizures. 15153780

2005

Entrez Id: 2550
Gene Symbol: GABBR1
GABBR1
CUI: C0270824
Disease: Visual seizure
Visual seizure
0.200 Biomarker RGD GABA receptor proteins within lipid rafts in the AY-9944 model of atypical absence seizures. 19054408

2009

Entrez Id: 2596
Gene Symbol: GAP43
GAP43
CUI: C0270824
Disease: Visual seizure
Visual seizure
0.200 Biomarker RGD Differential regulation of primary protein kinase C substrate (MARCKS, MLP, GAP-43, RC3) mRNAs in the hippocampus during kainic acid-induced seizures and synaptic reorganization. 11054811

2000

Entrez Id: 2697
Gene Symbol: GJA1
GJA1
CUI: C0270824
Disease: Visual seizure
Visual seizure
0.200 Biomarker RGD Cellular expression of connexins in the rat brain: neuronal localization, effects of kainate-induced seizures and expression in apoptotic neuronal cells. 14622215

2003

Entrez Id: 10804
Gene Symbol: GJB6
GJB6
CUI: C0270824
Disease: Visual seizure
Visual seizure
0.200 Biomarker RGD Expression of connexin 30 and connexin 32 in hippocampus of rat during epileptogenesis in a kindling model of epilepsy. 23149765

2012

Entrez Id: 2746
Gene Symbol: GLUD1
GLUD1
CUI: C0270824
Disease: Visual seizure
Visual seizure
0.200 Biomarker RGD Altered activities of rat brain metabolic enzymes in electroconvulsive shock-induced seizures. 11240587

2001

Entrez Id: 2752
Gene Symbol: GLUL
GLUL
CUI: C0270824
Disease: Visual seizure
Visual seizure
0.200 Biomarker RGD Glutamate decarboxylase and GABA aminotransferase levels in different regions of rat brain on the onset of Leptazol induced convulsions. 21935729

2012