Source: RGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
CUI: C0948031
Disease: Primary Graft Dysfunction
Primary Graft Dysfunction 		0.210 Therapeutic RGD Intercellular adhesion molecule-1 blockade attenuates inflammatory response and improves microvascular perfusion in rat pancreas grafts. 22617707

2012
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
CUI: C0375359
Disease: Chronic left-sided ulcerative colitis
Chronic left-sided ulcerative colitis 		0.210 Biomarker RGD Ulcerative colitis exacerbates lipopolysaccharide-induced damage to the nigral dopaminergic system: potential risk factor in Parkinson`s disease. 20584104

2010
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5 		0.210 Biomarker RGD High-calorie diet with moderate protein restriction prevents cachexia and ameliorates oxidative stress, inflammation and proteinuria in experimental chronic kidney disease. 20820841

2010
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
CUI: C0022346
Disease: Icterus
Icterus 		0.210 Biomarker RGD Effects of Salvia miltiorrhiza on intercellular adhesion molecule 1 protein expression in the lungs of rats with severe acute pancreatitis or obstructive jaundice. 19034056

2009
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis 		0.210 Biomarker RGD Previous study showed that aerosolized signal transducer and activator of transcription-1 (STAT1) antisense oligodeoxynucleotide (ASON) inhibited the expression of STAT1 and ICAM-1 mRNA and protein in alveolar macrophages (AMs) and decreased the concentrations of TGF-beta, PDGF and TNF-alpha in bronchioalveolar lavage fluid (BALF) in bleomycin (BLM)-induced rat pulmonary fibrosis. 19254480

2009
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
CUI: C0948031
Disease: Primary Graft Dysfunction
Primary Graft Dysfunction 		0.210 Therapeutic RGD Antisense intercellular adhesion molecule-1 (ICAM-1) oligodeoxyribonucleotide delivered during organ preservation inhibits posttransplant ICAM-1 expression and reduces primary lung isograft failure. 10666412

2000
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
CUI: C0027697
Disease: Nephritis
Nephritis 		0.210 Therapeutic RGD Due to these results, ICAM-1 is considered to be a critical molecule involved in the pathogenesis of the leukocyte infiltration into the glomeruli in the heterologous phase of Masugi nephritis. 8773354

1996
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
CUI: C0160390
Disease: Injury of liver
Injury of liver 		0.200 Therapeutic RGD Protective Effect of Thalidomide on Liver Injury in Rats with Acute Pancreatitis via Inhibition of Oxidative Stress. 26586701

2015
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
CUI: C0009319
Disease: Colitis
Colitis 		0.200 Biomarker RGD A vegetal ALA-rich formula decreases the expression of ICAM-1, VCAM-1, and VEGFR-2 and independently of HO-1 in rats with TNBS-induced colitis. 22261574

2012
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
CUI: C0033687
Disease: Proteinuria
Proteinuria 		0.200 Biomarker RGD Effects of intercellular adhesion molecule-1 on renal damage in spontaneously hypertensive rats. 22681549

2012
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.200 Therapeutic RGD Erythropoietin attenuates cardiopulmonary bypass-induced renal inflammatory injury by inhibiting nuclear factor-κB p65 expression. 22659586

2012
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack 		0.200 Therapeutic RGD [Effect of eye-acupuncture on cerebral intracellular adhesion molecule-1 expression in rats with acute cerebral ischemia-reperfusion injury]. 22379785

2011
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
CUI: C0020192
Disease: Hyaline Membrane Disease
Hyaline Membrane Disease 		0.200 Biomarker RGD Pre-treatment with glutamine attenuates lung injury in rats subjected to intestinal ischaemia-reperfusion. 19837405

2011
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy 		0.200 Biomarker RGD Dynamic changes of ICAM-1 expression in peripheral nervous system following sciatic nerve injury. 20546684

2011
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
CUI: C0267941
Disease: Pancreatitis, Acute Necrotizing
Pancreatitis, Acute Necrotizing 		0.200 Biomarker RGD The protective effects of Lipoxin A4 during the early phase of severe acute pancreatitis in rats. 20950211

2011
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
CUI: C0006110
Disease: Brain Death
Brain Death 		0.200 Biomarker RGD Carbon monoxide inhalation decreased lung injury via anti-inflammatory and anti-apoptotic effects in brain death rats. 20810760

2010
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
CUI: C0007194
Disease: Hypertrophic Cardiomyopathy
Hypertrophic Cardiomyopathy 		0.200 Biomarker RGD The protective effect of thalidomide on left ventricular function in a rat model of diabetic cardiomyopathy. 20601373

2010
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
CUI: C0014335
Disease: Enteritis
Enteritis 		0.200 Biomarker RGD Curcumin protects intestinal mucosal barrier function of rat enteritis via activation of MKP-1 and attenuation of p38 and NF-κB activation. 20885979

2010
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
CUI: C0025427
Disease: Mercury Poisoning
Mercury Poisoning 		0.200 Biomarker RGD Protective effect of mycophenolate mofetil on mercuric chloride-induced nephrotoxicity in rats. 20508868

2010
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
CUI: C0026766
Disease: Multiple Organ Failure
Multiple Organ Failure 		0.200 Biomarker RGD Ulinastatin-mediated protection against zymosan-induced multiple organ dysfunction in rats. 20646933

2010
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
CUI: C0035344
Disease: Retinopathy of Prematurity
Retinopathy of Prematurity 		0.200 Biomarker RGD RILLKKMPSV influences the vasculature, neurons and glia, and (pro)renin receptor expression in the retina. 20368504

2010
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia 		0.200 Biomarker RGD Danshensu protects vascular endothelia in a rat model of hyperhomocysteinemia. 20871618

2010
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
CUI: C0600518
Disease: Choroidal Neovascularization
Choroidal Neovascularization 		0.200 Biomarker RGD Effect of sorafenib on experimental choroidal neovascularization in the rat. 20497436

2010
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
CUI: C0949658
Disease: Cardiomyopathy, Hypertrophic, Familial
Cardiomyopathy, Hypertrophic, Familial 		0.200 Biomarker RGD The protective effect of thalidomide on left ventricular function in a rat model of diabetic cardiomyopathy. 20601373

2010
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
CUI: C1527311
Disease: Brain Edema
Brain Edema 		0.200 Biomarker RGD The effects of Tanshinone IIA on blood-brain barrier and brain edema after transient middle cerebral artery occlusion in rats. 20570121

2010