| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
signal transducer and activator of transcription 3 | 0.320 | 0.923 | 1.00 |
|
disease | 0.400 | None | 0.990 | 199 | 2 | 1997 | 2020 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.400 | None | 0.959 | 171 | 3 | 1990 | 2020 | ||||||||
|
catenin beta 1 | 0.303 | 0.885 | 1.00 |
|
disease | 0.500 | None | 0.964 | 168 | 1 | 1995 | 2020 | ||||||||
|
checkpoint kinase 2 | 0.460 | 0.808 | 1.2E-24 |
|
disease | 0.700 | None | 0.952 | 165 | 23 | 2001 | 2019 | ||||||||
|
hypoxia inducible factor 1 subunit alpha | 0.327 | 0.923 | 0.98 |
|
disease | 0.400 | None | 0.970 | 165 | 4 | 2002 | 2020 | ||||||||
|
estrogen receptor 2 | 0.400 | 0.923 | 4.5E-08 |
|
disease | 0.400 | None | 0.969 | 160 | 8 | 1996 | 2020 | ||||||||
|
interleukin 6 | 0.248 | 0.962 | 0.32 |
|
disease | 0.400 | None | 0.961 | 153 | 5 | 1996 | 2020 | ||||||||
|
transforming growth factor beta 1 | 0.287 | 0.962 | 3.7E-02 |
|
disease | 0.100 | None | 0.947 | 152 | 7 | 1990 | 2019 | ||||||||
|
partner and localizer of BRCA2 | 0.485 | 0.769 | 3.0E-19 |
|
disease | 0.700 | None | 0.961 | 152 | 21 | 2007 | 2020 | ||||||||
|
C-X-C motif chemokine receptor 4 | 0.362 | 0.923 | 1.8E-02 |
|
disease | 0.400 | None | 0.979 | 142 | 5 | 2002 | 2020 | ||||||||
|
fibroblast growth factor receptor 2 | 0.380 | 0.808 | 1.00 |
|
disease | 0.500 | None | 0.943 | 141 | 21 | 1996 | 2020 | ||||||||
|
MYC proto-oncogene, bHLH transcription factor | 0.344 | 0.923 | 1.00 |
|
disease | 0.100 | None | 0.978 | 139 | 1 | 1986 | 2020 | ||||||||
|
microRNA 21 | 0.363 | 0.846 |
|
disease | 0.100 | None | 0.993 | 136 | 0 | 2007 | 2020 | |||||||||
|
matrix metallopeptidase 9 | 0.305 | 0.923 | 1.9E-17 |
|
disease | 0.400 | None | 1.000 | 136 | 7 | 1996 | 2020 | ||||||||
|
vitamin D receptor | 0.352 | 0.885 | 1.7E-05 |
|
disease | 0.400 | None | 0.909 | 132 | 8 | 1994 | 2019 | ||||||||
|
prolactin | 0.406 | 0.885 | 2.9E-07 |
|
disease | 0.100 | None | 0.961 | 127 | 1 | 1975 | 2019 | ||||||||
|
CD274 molecule | 0.324 | 0.923 | 1.9E-02 |
|
disease | 0.100 | None | 0.952 | 124 | 0 | 2010 | 2020 | ||||||||
|
cyclin dependent kinase 4 | 0.412 | 0.808 | 6.3E-02 |
|
disease | 0.100 | None | 0.992 | 121 | 0 | 1995 | 2020 | ||||||||
|
cyclin dependent kinase inhibitor 2A | 0.300 | 0.885 | 0.39 |
|
disease | 0.500 | None | 0.899 | 119 | 5 | 1994 | 2020 | ||||||||
|
cytochrome P450 family 2 subfamily D member 6 | 0.437 | 0.885 | 1.1E-25 |
|
disease | 0.400 | None | 0.940 | 117 | 1 | 1996 | 2020 | ||||||||
|
leptin | 0.349 | 0.846 | 0.46 |
|
disease | 0.400 | None | 0.948 | 116 | 0 | 1999 | 2020 | ||||||||
|
mitogen-activated protein kinase 1 | 0.330 | 0.923 | 1.00 |
|
disease | 0.100 | None | 1.000 | 116 | 0 | 1996 | 2019 | ||||||||
|
cytochrome c oxidase subunit II | 0.352 | 0.962 |
|
disease | 0.100 | None | 0.957 | 115 | 0 | 1998 | 2019 | |||||||||
|
poly(ADP-ribose) polymerase 1 | 0.389 | 0.923 | 3.3E-04 |
|
disease | 0.400 | None | 0.964 | 112 | 7 | 1996 | 2020 | ||||||||
|
MDM2 proto-oncogene | 0.362 | 0.846 | 1.00 |
|
disease | 0.500 | None | 0.922 | 102 | 6 | 1993 | 2019 |