Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 8826
Gene Symbol: IQGAP1
IQGAP1
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.010 AlteredExpression LHGDN IQGAP1 expression level seemed to be closely associated with the enhanced invasion and migration in ovarian cancer cell lines. 19036171

2008

Entrez Id: 54940
Gene Symbol: OCIAD1
OCIAD1
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.010 AlteredExpression LHGDN This is the first report that OCIAD1 is over-expressed in metastatic ovarian cancer tissues. 18328549

2008

Entrez Id: 5829
Gene Symbol: PXN
PXN
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.010 Biomarker LHGDN Activation of platelet-activating factor receptor and pleiotropic effects on tyrosine phospho-EGFR/Src/FAK/paxillin in ovarian cancer. 18632638

2008

Entrez Id: 3698
Gene Symbol: ITIH2
ITIH2
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.010 Biomarker LHGDN Role of serum-derived hyaluronan-associated protein-hyaluronan complex in ovarian cancer. 18425383

2008

Entrez Id: 967
Gene Symbol: CD63
CD63
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.010 AlteredExpression LHGDN There is low expression of the proteins and mRNA of ME491/CD63 and integrin alpha5 in ovarian cancer. 17624082

2007

Entrez Id: 7216
Gene Symbol: TRO
TRO
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.010 AlteredExpression LHGDN Trophinin is a potent prognostic marker of ovarian cancer involved in platinum sensitivity. 17597582

2007

Entrez Id: 5720
Gene Symbol: PSME1
PSME1
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.010 Biomarker LHGDN Specific MALDI imaging and profiling for biomarker hunting and validation: fragment of the 11S proteasome activator complex, Reg alpha fragment, is a new potential ovary cancer biomarker. 17939699

2007

Entrez Id: 43
Gene Symbol: ACHE
ACHE
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.010 AlteredExpression LHGDN Both cytoplasmic ACHE and BACH2 immunostaining were significantly increased in ovarian cancer relative to benign cases. 16832351

2007

Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.010 Biomarker LHGDN Taken together, our results support a pro-proliferative and pro-survival role for HOXB13 in ovarian cancer. 17942676

2007

Entrez Id: 1394
Gene Symbol: CRHR1
CRHR1
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.010 Biomarker LHGDN These findings support the hypothesis that CRHR1 antagonists could potentially be used against ovarian cancer. 17667919

2007

Entrez Id: 144455
Gene Symbol: E2F7
E2F7
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.010 AlteredExpression LHGDN Clinical relevance of E2F family members in ovarian cancer--an evaluation in a training set of 77 patients. 17200349

2007

Entrez Id: 60468
Gene Symbol: BACH2
BACH2
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.010 AlteredExpression LHGDN Both cytoplasmic ACHE and BACH2 immunostaining were significantly increased in ovarian cancer relative to benign cases. 16832351

2007

Entrez Id: 5155
Gene Symbol: PDGFB
PDGFB
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.010 Biomarker LHGDN PDGF BB induces VEGF secretion in ovarian cancer. 18075302

2007

Entrez Id: 2050
Gene Symbol: EPHB4
EPHB4
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.010 AlteredExpression LHGDN Treatment of malignant, but not benign, ovarian tumour cell lines with progesterone, but not oestrogen, led to a 90% reduction in EphB4 levels that was associated with 50% reduction in cell survival. 17353927

2007

Entrez Id: 63928
Gene Symbol: CHP2
CHP2
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.010 AlteredExpression LHGDN The current study provides the first evidence that overexpression of the CHP2 gene affects the biological behavior of ovarian cancer cell line OVCAR3 and is one of key mechanisms for ovarian carcinoma progression, suggesting that CHP2 may be an attractive target for biological anticancer therapy. 17708351

2007

Entrez Id: 5605
Gene Symbol: MAP2K2
MAP2K2
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.010 GeneticVariation LHGDN Fifteen ovarian cancer cell lines, commonly used for in vitro experiments, were screened for mutations using bidirectional direct sequencing in all coding regions of BRAF, MEK1 and MEK2. 18060073

2007

Entrez Id: 6286
Gene Symbol: S100P
S100P
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.010 AlteredExpression LHGDN Unfavourable prognostic significance of S100P expression in ovarian cancers. 17539915

2007

Entrez Id: 3640
Gene Symbol: INSL3
INSL3
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.010 AlteredExpression LHGDN Elevated plasma levels of the novel hormone INSL3 in a woman with metastatic ovarian cancer. 17549672

2007

Entrez Id: 1392
Gene Symbol: CRH
CRH
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.010 Biomarker LHGDN Corticotropin-releasing hormone produced by human ovarian cancer might favour survival and progression of the tumour by promoting its immune privilege. 17667919

2007

Entrez Id: 768
Gene Symbol: CA9
CA9
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.010 AlteredExpression LHGDN MN/CA9: a potential gene marker for detection of malignant cells in effusions. 17536770

2007

Entrez Id: 3291
Gene Symbol: HSD11B2
HSD11B2
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.010 AlteredExpression LHGDN Type 2 11beta-hydroxysteroid dehydrogenase activity in human ovarian cancer. 17028049

2006

Entrez Id: 3598
Gene Symbol: IL13RA2
IL13RA2
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.010 AlteredExpression LHGDN Immunohistochemical analyses revealed that 83% of ovarian cancer specimens express IL-13Ralpha2, a high-affinity IL-13R subunit chain, whereas normal ovary samples expressed none or very low levels. 16902988

2006

Entrez Id: 157310
Gene Symbol: PEBP4
PEBP4
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.010 Biomarker LHGDN Anti-apoptotic hPEBP4 silencing promotes TRAIL-induced apoptosis of human ovarian cancer cells by activating ERK and JNK pathways. 16865237

2006

Entrez Id: 2664
Gene Symbol: GDI1
GDI1
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.010 AlteredExpression LHGDN Gene expression profiles with cDNA microarray reveal RhoGDI as a predictive marker for paclitaxel resistance in ovarian cancers. 16596196

2006

Entrez Id: 2706
Gene Symbol: GJB2
GJB2
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.010 Biomarker LHGDN Loss of communication in ovarian cancer. 16647893

2006