Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.200 Therapeutic RGD Caspase-dependent and caspase-independent induction of apoptosis in breast cancer by fucoidan via the PI3K/AKT/GSK3β pathway in vivo and in vitro. 28810530

2017

Entrez Id: 842
Gene Symbol: CASP9
CASP9
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.200 Therapeutic RGD Pomegranate exerts chemoprevention of experimentally induced mammary tumorigenesis by suppression of cell proliferation and induction of apoptosis. 26699876

2016

Entrez Id: 840
Gene Symbol: CASP7
CASP7
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.200 Therapeutic RGD Pomegranate exerts chemoprevention of experimentally induced mammary tumorigenesis by suppression of cell proliferation and induction of apoptosis. 26699876

2016

Entrez Id: 836
Gene Symbol: CASP3
CASP3
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.200 Therapeutic RGD Pomegranate exerts chemoprevention of experimentally induced mammary tumorigenesis by suppression of cell proliferation and induction of apoptosis. 26699876

2016

Entrez Id: 1789
Gene Symbol: DNMT3B
DNMT3B
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.200 Therapeutic RGD Methylation and miRNA effects of resveratrol on mammary tumors vs. normal tissue. 24447120

2014

Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.200 Therapeutic RGD Chemopreventive effect of a novel oleanane triterpenoid in a chemically induced rodent model of breast cancer. 23404339

2013

Entrez Id: 840
Gene Symbol: CASP7
CASP7
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.200 Therapeutic RGD Chemopreventive effect of a novel oleanane triterpenoid in a chemically induced rodent model of breast cancer. 23404339

2013

Entrez Id: 581
Gene Symbol: BAX
BAX
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.200 Therapeutic RGD Chemopreventive effect of a novel oleanane triterpenoid in a chemically induced rodent model of breast cancer. 23404339

2013

Entrez Id: 598
Gene Symbol: BCL2L1
BCL2L1
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.200 Therapeutic RGD Chemopreventive effect of a novel oleanane triterpenoid in a chemically induced rodent model of breast cancer. 23404339

2013

Entrez Id: 3240
Gene Symbol: HP
HP
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.200 Therapeutic RGD Proteomic changes induced by effective chemopreventive ratios of n-3:n-6 fatty acids and tamoxifen against MNU-induced mammary cancer in the rat. 23880232

2013

Entrez Id: 836
Gene Symbol: CASP3
CASP3
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.200 Therapeutic RGD Chemopreventive effect of a novel oleanane triterpenoid in a chemically induced rodent model of breast cancer. 23404339

2013

Entrez Id: 142
Gene Symbol: PARP1
PARP1
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.200 Therapeutic RGD Chemopreventive effect of a novel oleanane triterpenoid in a chemically induced rodent model of breast cancer. 23404339

2013

Entrez Id: 572
Gene Symbol: BAD
BAD
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.200 Therapeutic RGD Chemopreventive effect of a novel oleanane triterpenoid in a chemically induced rodent model of breast cancer. 23404339

2013

Entrez Id: 2475
Gene Symbol: MTOR
MTOR
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.200 Biomarker RGD Critical role of arachidonic acid-activated mTOR signaling in breast carcinogenesis and angiogenesis. 22349822

2013

Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.200 Therapeutic RGD Identification of a molecular signature underlying inhibition of mammary carcinoma growth by dietary N-3 fatty acids. 22651929

2012

Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.200 Therapeutic RGD Effects of energy restriction and wheel running on mammary carcinogenesis and host systemic factors in a rat model. 22246620

2012

Entrez Id: 5300
Gene Symbol: PIN1
PIN1
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.200 Biomarker RGD Regulation of estrogen receptor α N-terminus conformation and function by peptidyl prolyl isomerase Pin1. 22064478

2012

Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.200 Therapeutic RGD Immunohistochemical and histomorphological analysis of rat mammary tumors after simvastatin treatment. 22668016

2012

Entrez Id: 3952
Gene Symbol: LEP
LEP
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.200 Therapeutic RGD Effects of energy restriction and wheel running on mammary carcinogenesis and host systemic factors in a rat model. 22246620

2012

Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.200 Therapeutic RGD Induction of NAD(P)H-quinone oxidoreductase 1 by antioxidants in female ACI rats is associated with decrease in oxidative DNA damage and inhibition of estrogen-induced breast cancer. 22072621

2012

Entrez Id: 836
Gene Symbol: CASP3
CASP3
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.200 ModifyingMutation RGD Long-term hormonal promotion overcomes genetic resistance to mammary cancer. 20732338

2011

Entrez Id: 841
Gene Symbol: CASP8
CASP8
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.200 ModifyingMutation RGD Long-term hormonal promotion overcomes genetic resistance to mammary cancer. 20732338

2011

Entrez Id: 842
Gene Symbol: CASP9
CASP9
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.200 ModifyingMutation RGD Long-term hormonal promotion overcomes genetic resistance to mammary cancer. 20732338

2011

Entrez Id: 3690
Gene Symbol: ITGB3
ITGB3
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.200 Biomarker RGD Quantification of epithelial cell differentiation in mammary glands and carcinomas from DMBA- and MNU-exposed rats. 22022542

2011

Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.200 Biomarker RGD Study on cow ghee versus soybean oil on 7,12-dimethylbenz(a)-anthracene induced mammary carcinogenesis & expression of cyclooxygenase-2 & peroxisome proliferators activated receptor-γ in rats. 21623034

2011