×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
Mammary Neoplasms
0.700
GeneticVariation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011
2016
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
Mammary Neoplasms
0.700
GeneticVariation
CLINVAR
Mutations in residues of TP53 that directly contact DNA predict poor outcome in human primary breast cancer.
9569050
1998
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
Mammary Neoplasms
0.700
GeneticVariation
CLINVAR
The clinical value of somatic TP53 gene mutations in 1,794 patients with breast cancer.
16489069
2006
×
Entrez Id:
2475
Gene Symbol:
MTOR
MTOR
Mammary Neoplasms
0.500
GeneticVariation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011
2016
×
Entrez Id:
2099
Gene Symbol:
ESR1
ESR1
Mammary Neoplasms
0.500
GeneticVariation
CLINVAR
Emergence of constitutively active estrogen receptor-α mutations in pretreated advanced estrogen receptor-positive breast cancer.
24398047
2014
×
Entrez Id:
2065
Gene Symbol:
ERBB3
ERBB3
Mammary Neoplasms
0.500
GeneticVariation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011
2016
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Mammary Neoplasms
0.500
GeneticVariation
CLINVAR
Genetic and functional analysis of CHEK2 (CHK2) variants in multiethnic cohorts.
17721994
2007
×
Entrez Id:
2064
Gene Symbol:
ERBB2
ERBB2
Mammary Neoplasms
0.500
GeneticVariation
CLINVAR
Differential sensitivity of ERBB2 kinase domain mutations towards lapatinib.
22046346
2011
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Mammary Neoplasms
0.500
GeneticVariation
CLINVAR
Comprehensive analysis of missense variations in the BRCT domain of BRCA1 by structural and functional assays.
20516115
2010
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Mammary Neoplasms
0.500
GeneticVariation
CLINVAR
CHEK2 contribution to hereditary breast cancer in non-BRCA families.
22114986
2011
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Mammary Neoplasms
0.500
GeneticVariation
CLINVAR
Does familial breast cancer and thymoma suggest a cancer syndrome? A family perspective.
26344711
2015
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Mammary Neoplasms
0.500
GeneticVariation
CLINVAR
Prevalence and Prognostic Role of BRCA1/2 Variants in Unselected Chinese Breast Cancer Patients.
27257965
2016
×
Entrez Id:
2064
Gene Symbol:
ERBB2
ERBB2
Mammary Neoplasms
0.500
GeneticVariation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011
2016
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
Mammary Neoplasms
0.500
GeneticVariation
CLINVAR
Prevalence and Prognostic Role of BRCA1/2 Variants in Unselected Chinese Breast Cancer Patients.
27257965
2016
×
Entrez Id:
2263
Gene Symbol:
FGFR2
FGFR2
Mammary Neoplasms
0.500
GeneticVariation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011
2016
×
Entrez Id:
2064
Gene Symbol:
ERBB2
ERBB2
Mammary Neoplasms
0.500
GeneticVariation
CLINVAR
Response of an ERBB2-mutated inflammatory breast carcinoma to human epidermal growth factor receptor 2-targeted therapy.
24516025
2014
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
Mammary Neoplasms
0.500
GeneticVariation
CLINVAR
Prospective enterprise-level molecular genotyping of a cohort of cancer patients.
25157968
2014
×
Entrez Id:
2064
Gene Symbol:
ERBB2
ERBB2
Mammary Neoplasms
0.500
GeneticVariation
CLINVAR
Activating HER2 mutations in HER2 gene amplification negative breast cancer.
23220880
2013
×
Entrez Id:
2064
Gene Symbol:
ERBB2
ERBB2
Mammary Neoplasms
0.500
GeneticVariation
CLINVAR
Prospective enterprise-level molecular genotyping of a cohort of cancer patients.
25157968
2014
×
Entrez Id:
2064
Gene Symbol:
ERBB2
ERBB2
Mammary Neoplasms
0.500
GeneticVariation
CLINVAR
EXEL-7647 inhibits mutant forms of ErbB2 associated with lapatinib resistance and neoplastic transformation.
18413839
2008
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
Mammary Neoplasms
0.500
GeneticVariation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011
2016
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
Mammary Neoplasms
0.500
GeneticVariation
CLINVAR
We identified PIK3CA mutations in 26% of 342 human breast tumor samples and cell lines at about equal frequency in tumor stages I to IV.
15805248
2005
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
Mammary Neoplasms
0.500
GeneticVariation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011
2016
×
Entrez Id:
2099
Gene Symbol:
ESR1
ESR1
Mammary Neoplasms
0.500
GeneticVariation
CLINVAR
We conducted a comprehensive genetic analysis of two independent cohorts of metastatic ER-positive breast tumors and identified mutations in ESR1 affecting the ligand-binding domain (LBD) in 14 of 80 cases.
24185512
2013
×
Entrez Id:
2099
Gene Symbol:
ESR1
ESR1
Mammary Neoplasms
0.500
GeneticVariation
CLINVAR
Activating ESR1 mutations in hormone-resistant metastatic breast cancer.
24185510
2013