×
Entrez Id:
1048
Gene Symbol:
CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
Carcinoembryonic antigen (CEA ) is the most widely used tumor marker for colorectal cancer .
1290028
1992
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
These results support that p53 gene plays an important role in the development of colorectal cancer .
1306299
1992
×
Entrez Id:
5906
Gene Symbol:
RAP1A
RAP1A
Malignant neoplasm of colon and/or rectum
0.010
GeneticVariation
BEFREE
This suggests that loss of heterozygosity is not a common mechanism of inactivation at the Krev-1 locus in colorectal cancer .
1345809
1992
×
Entrez Id:
6175
Gene Symbol:
RPLP0
RPLP0
Malignant neoplasm of colon and/or rectum
0.020
AlteredExpression
BEFREE
These findings support a common increased expression of selected gene products in different tumors of endodermal origin and suggest that increased P0 expression, in line with certain other ribosomal proteins, may be associated with human colorectal cancer progression and biological aggressiveness.
1350508
1992
×
Entrez Id:
1048
Gene Symbol:
CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
Application of genetically-engineered anti-CEA antibodies for potential immunotherapy of colorectal cancer .
1431347
1992
×
Entrez Id:
5670
Gene Symbol:
PSG2
PSG2
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
Application of genetically-engineered anti-CEA antibodies for potential immunotherapy of colorectal cancer .
1431347
1992
×
Entrez Id:
1087
Gene Symbol:
CEACAM7
CEACAM7
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
Application of genetically-engineered anti-CEA antibodies for potential immunotherapy of colorectal cancer .
1431347
1992
×
Entrez Id:
1084
Gene Symbol:
CEACAM3
CEACAM3
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
Application of genetically-engineered anti-CEA antibodies for potential immunotherapy of colorectal cancer .
1431347
1992
×
Entrez Id:
5423
Gene Symbol:
POLB
POLB
Malignant neoplasm of colon and/or rectum
0.030
GeneticVariation
BEFREE
DNA polymerase beta mutations in human colorectal cancer .
1511447
1992
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
Allelic loss was studied for chromosomes 5, 17, and 18, and immunohistochemical analysis was done of the p53 protein product in tumors from 91 patients with colorectal cancer .
1516028
1992
×
Entrez Id:
1630
Gene Symbol:
DCC
DCC
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
Inactivation of the DCC gene on chromosome 18 owing to loss of heterozygosity is a common finding in colorectal cancer .
1594239
1992
×
Entrez Id:
4163
Gene Symbol:
MCC
MCC
Malignant neoplasm of colon and/or rectum
0.090
GeneticVariation
BEFREE
MCC is a gene located within human chromosome band 5q.21 that shows somatically acquired mutations in colorectal cancer , and may be identical to the gene responsible for inheritance of familial adenomatous polyposis.
1656365
1991
×
Entrez Id:
4830
Gene Symbol:
NME1
NME1
Malignant neoplasm of colon and/or rectum
0.090
GeneticVariation
BEFREE
A prospective study analysed the prognostic value of nm23-H1 allelic deletions in colorectal cancer .
1679868
1991
×
Entrez Id:
3265
Gene Symbol:
HRAS
HRAS
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
Distribution of Ha-ras alleles in patients with colorectal cancer and Crohn's disease.
1685466
1991
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
Mutation of the p53 gene is one of the commonest genetic changes in the development of human colorectal cancer .
1699228
1990
×
Entrez Id:
4609
Gene Symbol:
MYC
MYC
Malignant neoplasm of colon and/or rectum
0.100
AlteredExpression
BEFREE
The expression of the c-myc protein product (p62 c-myc) and deoxyribonucleic acid (DNA) ploidy status was determined by a flow cytometric technique in 83 patients with colorectal cancer followed up for a median of 30 months (range 6-60 months).
1874294
1991
×
Entrez Id:
8878
Gene Symbol:
SQSTM1
SQSTM1
Malignant neoplasm of colon and/or rectum
0.040
AlteredExpression
BEFREE
Use of the OM-11-906 monoclonal antibody for determining p62 c-myc expression by flow cytometry in relation to prognosis in colorectal cancer .
1874294
1991
×
Entrez Id:
10657
Gene Symbol:
KHDRBS1
KHDRBS1
Malignant neoplasm of colon and/or rectum
0.040
AlteredExpression
BEFREE
Use of the OM-11-906 monoclonal antibody for determining p62 c-myc expression by flow cytometry in relation to prognosis in colorectal cancer .
1874294
1991
×
Entrez Id:
51164
Gene Symbol:
DCTN4
DCTN4
Malignant neoplasm of colon and/or rectum
0.030
AlteredExpression
BEFREE
Use of the OM-11-906 monoclonal antibody for determining p62 c-myc expression by flow cytometry in relation to prognosis in colorectal cancer .
1874294
1991
×
Entrez Id:
2965
Gene Symbol:
GTF2H1
GTF2H1
Malignant neoplasm of colon and/or rectum
0.030
AlteredExpression
BEFREE
Use of the OM-11-906 monoclonal antibody for determining p62 c-myc expression by flow cytometry in relation to prognosis in colorectal cancer .
1874294
1991
×
Entrez Id:
23636
Gene Symbol:
NUP62
NUP62
Malignant neoplasm of colon and/or rectum
0.030
AlteredExpression
BEFREE
Use of the OM-11-906 monoclonal antibody for determining p62 c-myc expression by flow cytometry in relation to prognosis in colorectal cancer .
1874294
1991
×
Entrez Id:
324
Gene Symbol:
APC
APC
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
These data not only allow use of flanking markers for presymptomatic diagnosis of FAP but also provide a high-density map of the region for isolation of the APC gene itself and for further assessment of the role of chromosome 5 deletions in the biology of sporadic colorectal cancer .
1978564
1990
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
A novel point mutation at codon 146 of the K-ras gene in a human colorectal cancer identified by the polymerase chain reaction.
2017878
1991
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
Malignant neoplasm of colon and/or rectum
0.100
AlteredExpression
BEFREE
This dual parameter flow cytometric method, evaluating both DNA ploidy and p53 expression, may prove useful in identifying different biological subgroups of colorectal cancer .
2137812
1990
×
Entrez Id:
3958
Gene Symbol:
LGALS3
LGALS3
Malignant neoplasm of colon and/or rectum
0.100
AlteredExpression
BEFREE
Our results suggest that mRNA expression of the laminin-binding protein may be a marker of human colorectal cancer progression and biological aggressiveness.
2141294
1990