Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE Carcinoembryonic antigen (CEA) is the most widely used tumor marker for colorectal cancer. 1290028

1992

Entrez Id: 7157
Gene Symbol: TP53
TP53
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE These results support that p53 gene plays an important role in the development of colorectal cancer. 1306299

1992

Entrez Id: 5906
Gene Symbol: RAP1A
RAP1A
Malignant neoplasm of colon and/or rectum
0.010 GeneticVariation BEFREE This suggests that loss of heterozygosity is not a common mechanism of inactivation at the Krev-1 locus in colorectal cancer. 1345809

1992

Entrez Id: 6175
Gene Symbol: RPLP0
RPLP0
Malignant neoplasm of colon and/or rectum
0.020 AlteredExpression BEFREE These findings support a common increased expression of selected gene products in different tumors of endodermal origin and suggest that increased P0 expression, in line with certain other ribosomal proteins, may be associated with human colorectal cancer progression and biological aggressiveness. 1350508

1992

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE Application of genetically-engineered anti-CEA antibodies for potential immunotherapy of colorectal cancer. 1431347

1992

Entrez Id: 5670
Gene Symbol: PSG2
PSG2
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE Application of genetically-engineered anti-CEA antibodies for potential immunotherapy of colorectal cancer. 1431347

1992

Entrez Id: 1087
Gene Symbol: CEACAM7
CEACAM7
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE Application of genetically-engineered anti-CEA antibodies for potential immunotherapy of colorectal cancer. 1431347

1992

Entrez Id: 1084
Gene Symbol: CEACAM3
CEACAM3
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE Application of genetically-engineered anti-CEA antibodies for potential immunotherapy of colorectal cancer. 1431347

1992

Entrez Id: 5423
Gene Symbol: POLB
POLB
Malignant neoplasm of colon and/or rectum
0.030 GeneticVariation BEFREE DNA polymerase beta mutations in human colorectal cancer. 1511447

1992

Entrez Id: 7157
Gene Symbol: TP53
TP53
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE Allelic loss was studied for chromosomes 5, 17, and 18, and immunohistochemical analysis was done of the p53 protein product in tumors from 91 patients with colorectal cancer. 1516028

1992

Entrez Id: 1630
Gene Symbol: DCC
DCC
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation BEFREE Inactivation of the DCC gene on chromosome 18 owing to loss of heterozygosity is a common finding in colorectal cancer. 1594239

1992

Entrez Id: 4163
Gene Symbol: MCC
MCC
Malignant neoplasm of colon and/or rectum
0.090 GeneticVariation BEFREE MCC is a gene located within human chromosome band 5q.21 that shows somatically acquired mutations in colorectal cancer, and may be identical to the gene responsible for inheritance of familial adenomatous polyposis. 1656365

1991

Entrez Id: 4830
Gene Symbol: NME1
NME1
Malignant neoplasm of colon and/or rectum
0.090 GeneticVariation BEFREE A prospective study analysed the prognostic value of nm23-H1 allelic deletions in colorectal cancer. 1679868

1991

Entrez Id: 3265
Gene Symbol: HRAS
HRAS
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation BEFREE Distribution of Ha-ras alleles in patients with colorectal cancer and Crohn's disease. 1685466

1991

Entrez Id: 7157
Gene Symbol: TP53
TP53
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation BEFREE Mutation of the p53 gene is one of the commonest genetic changes in the development of human colorectal cancer. 1699228

1990

Entrez Id: 4609
Gene Symbol: MYC
MYC
Malignant neoplasm of colon and/or rectum
0.100 AlteredExpression BEFREE The expression of the c-myc protein product (p62 c-myc) and deoxyribonucleic acid (DNA) ploidy status was determined by a flow cytometric technique in 83 patients with colorectal cancer followed up for a median of 30 months (range 6-60 months). 1874294

1991

Entrez Id: 8878
Gene Symbol: SQSTM1
SQSTM1
Malignant neoplasm of colon and/or rectum
0.040 AlteredExpression BEFREE Use of the OM-11-906 monoclonal antibody for determining p62 c-myc expression by flow cytometry in relation to prognosis in colorectal cancer. 1874294

1991

Entrez Id: 10657
Gene Symbol: KHDRBS1
KHDRBS1
Malignant neoplasm of colon and/or rectum
0.040 AlteredExpression BEFREE Use of the OM-11-906 monoclonal antibody for determining p62 c-myc expression by flow cytometry in relation to prognosis in colorectal cancer. 1874294

1991

Entrez Id: 51164
Gene Symbol: DCTN4
DCTN4
Malignant neoplasm of colon and/or rectum
0.030 AlteredExpression BEFREE Use of the OM-11-906 monoclonal antibody for determining p62 c-myc expression by flow cytometry in relation to prognosis in colorectal cancer. 1874294

1991

Entrez Id: 2965
Gene Symbol: GTF2H1
GTF2H1
Malignant neoplasm of colon and/or rectum
0.030 AlteredExpression BEFREE Use of the OM-11-906 monoclonal antibody for determining p62 c-myc expression by flow cytometry in relation to prognosis in colorectal cancer. 1874294

1991

Entrez Id: 23636
Gene Symbol: NUP62
NUP62
Malignant neoplasm of colon and/or rectum
0.030 AlteredExpression BEFREE Use of the OM-11-906 monoclonal antibody for determining p62 c-myc expression by flow cytometry in relation to prognosis in colorectal cancer. 1874294

1991

Entrez Id: 324
Gene Symbol: APC
APC
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation BEFREE These data not only allow use of flanking markers for presymptomatic diagnosis of FAP but also provide a high-density map of the region for isolation of the APC gene itself and for further assessment of the role of chromosome 5 deletions in the biology of sporadic colorectal cancer. 1978564

1990

Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation BEFREE A novel point mutation at codon 146 of the K-ras gene in a human colorectal cancer identified by the polymerase chain reaction. 2017878

1991

Entrez Id: 7157
Gene Symbol: TP53
TP53
Malignant neoplasm of colon and/or rectum
0.100 AlteredExpression BEFREE This dual parameter flow cytometric method, evaluating both DNA ploidy and p53 expression, may prove useful in identifying different biological subgroups of colorectal cancer. 2137812

1990

Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
Malignant neoplasm of colon and/or rectum
0.100 AlteredExpression BEFREE Our results suggest that mRNA expression of the laminin-binding protein may be a marker of human colorectal cancer progression and biological aggressiveness. 2141294

1990