×
Entrez Id:
7148
Gene Symbol:
TNXB
TNXB
Lupus Erythematosus, Systemic
0.130
GeneticVariation
GWASDB
Our findings strongly imply that the TNXB gene is a candidate gene susceptible to SLE in the Japanese population.
18058064
2008
×
Entrez Id:
640
Gene Symbol:
BLK
BLK
Lupus Erythematosus, Systemic
0.700
GeneticVariation
GWASDB
We identified and then confirmed through replication two new genetic loci for SLE : a promoter-region allele associated with reduced expression of BLK and increased expression of C8orf13 and variants in the ITGAM-ITGAX region.
18204098
2008
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Lupus Erythematosus, Systemic
0.700
GeneticVariation
GWASDB
Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX.
18204098
2008
HLA-DQA1
Lupus Erythematosus, Systemic
0.500
GeneticVariation
GWASDB
Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX.
18204098
2008
×
Entrez Id:
3687
Gene Symbol:
ITGAX
ITGAX
Lupus Erythematosus, Systemic
0.150
GeneticVariation
GWASDB
Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX.
18204098
2008
HLA-DQA2
Lupus Erythematosus, Systemic
0.110
GeneticVariation
GWASDB
Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX.
18204098
2008
×
Entrez Id:
3684
Gene Symbol:
ITGAM
ITGAM
Lupus Erythematosus, Systemic
0.700
GeneticVariation
GWASDB
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.
18204446
2008
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Lupus Erythematosus, Systemic
0.700
GeneticVariation
GWASDB
We also found evidence for association (P < 1 x 10(-5)) at FCGR2A, PTPN22 and STAT4 , regions previously associated with SLE and other autoimmune diseases, as well as at > or =9 other loci (P < 2 x 10(-7)).
18204446
2008
×
Entrez Id:
640
Gene Symbol:
BLK
BLK
Lupus Erythematosus, Systemic
0.700
GeneticVariation
GWASDB
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.
18204446
2008
×
Entrez Id:
54899
Gene Symbol:
PXK
PXK
Lupus Erythematosus, Systemic
0.670
GeneticVariation
GWASDB
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.
18204446
2008
×
Entrez Id:
2212
Gene Symbol:
FCGR2A
FCGR2A
Lupus Erythematosus, Systemic
0.500
GeneticVariation
GWASDB
We also found evidence for association (P < 1 x 10(-5)) at FCGR2A , PTPN22 and STAT4, regions previously associated with SLE and other autoimmune diseases, as well as at > or =9 other loci (P < 2 x 10(-7)).
18204446
2008
×
Entrez Id:
7332
Gene Symbol:
UBE2L3
UBE2L3
Lupus Erythematosus, Systemic
0.490
GeneticVariation
GWASDB
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.
18204446
2008
×
Entrez Id:
57661
Gene Symbol:
PHRF1
PHRF1
Lupus Erythematosus, Systemic
0.470
GeneticVariation
GWASDB
Aside from the expected strong association between SLE and the HLA region on chromosome 6p21 and the previously confirmed non-HLA locus IRF5 on chromosome 7q32, we found evidence of association with replication (1.1 x 10(-7) < P(overall) < 1.6 x 10(-23); odds ratio = 0.82-1.62) in four regions: 16p11.2 (ITGAM), 11p15.5 (KIAA1542 ), 3p14.3 (PXK) and 1q25.1 (rs10798269).
18204446
2008
×
Entrez Id:
629
Gene Symbol:
CFB
CFB
Lupus Erythematosus, Systemic
0.400
GeneticVariation
GWASDB
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.
18204446
2008
×
Entrez Id:
9474
Gene Symbol:
ATG5
ATG5
Lupus Erythematosus, Systemic
0.390
GeneticVariation
GWASDB
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.
18204446
2008
×
Entrez Id:
4067
Gene Symbol:
LYN
LYN
Lupus Erythematosus, Systemic
0.320
GeneticVariation
GWASDB
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.
18204446
2008
×
Entrez Id:
23534
Gene Symbol:
TNPO3
TNPO3
Lupus Erythematosus, Systemic
0.130
GeneticVariation
GWASDB
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.
18204446
2008
×
Entrez Id:
4439
Gene Symbol:
MSH5
MSH5
Lupus Erythematosus, Systemic
0.130
GeneticVariation
GWASDB
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.
18204446
2008
×
Entrez Id:
286046
Gene Symbol:
XKR6
XKR6
Lupus Erythematosus, Systemic
0.120
GeneticVariation
GWASDB
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.
18204446
2008
×
Entrez Id:
1589
Gene Symbol:
CYP21A2
CYP21A2
Lupus Erythematosus, Systemic
0.120
GeneticVariation
GWASDB
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.
18204446
2008
×
Entrez Id:
23057
Gene Symbol:
NMNAT2
NMNAT2
Lupus Erythematosus, Systemic
0.110
GeneticVariation
GWASDB
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.
18204446
2008
×
Entrez Id:
3122
Gene Symbol:
HLA-DRA
HLA-DRA
Lupus Erythematosus, Systemic
0.110
GeneticVariation
GWASDB
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.
18204446
2008
FAM167A-AS1
Lupus Erythematosus, Systemic
0.100
GeneticVariation
GWASDB
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.
18204446
2008
MSH5-SAPCD1
Lupus Erythematosus, Systemic
0.100
GeneticVariation
GWASDB
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.
18204446
2008
×
Entrez Id:
80274
Gene Symbol:
SCUBE1
SCUBE1
Lupus Erythematosus, Systemic
0.100
GeneticVariation
GWASDB
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.
18204446
2008