Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 85358
Gene Symbol: SHANK3
SHANK3
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.700 Biomarker CTD_human

Entrez Id: 65078
Gene Symbol: RTN4R
RTN4R
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.670 Biomarker CTD_human

Entrez Id: 6505
Gene Symbol: SLC1A1
SLC1A1
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.500 Biomarker CTD_human

Entrez Id: 1116
Gene Symbol: CHI3L1
CHI3L1
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.500 Biomarker CTD_human

Entrez Id: 27184
Gene Symbol: DISC2
DISC2
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.500 Biomarker CTD_human

Entrez Id: 267012
Gene Symbol: DAOA
DAOA
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.500 Biomarker CTD_human

Entrez Id: 6854
Gene Symbol: SYN2
SYN2
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.490 Biomarker CTD_human

Entrez Id: 23780
Gene Symbol: APOL2
APOL2
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.410 Biomarker CTD_human

Entrez Id: 80832
Gene Symbol: APOL4
APOL4
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.400 Biomarker CTD_human

Entrez Id: 1137
Gene Symbol: CHRNA4
CHRNA4
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.400 Biomarker PSYGENET α7 nicotinic receptor agonism mitigates phencyclidine-induced changes in synaptophysin and Arc gene expression in the mouse prefrontal cortex. 20817066

2010

Entrez Id: 3105
Gene Symbol: HLA-A
HLA-A
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.470 Biomarker PSYGENET β2 microglobulin, HLA-A and Notch4 were all expressed in a pattern where inflammatory illness was associated with increased expression in controls but not in subjects with schizophrenia. 23395714

2013

Entrez Id: 4855
Gene Symbol: NOTCH4
NOTCH4
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.500 Biomarker PSYGENET β2 microglobulin, HLA-A and Notch4 were all expressed in a pattern where inflammatory illness was associated with increased expression in controls but not in subjects with schizophrenia. 23395714

2013

Entrez Id: 54210
Gene Symbol: TREM1
TREM1
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.320 Biomarker PSYGENET 1.TREM-1 gene expression was increased in the monocytes of SCZ and BD patients and tended to be increased in the monocytes of MDD patients.2. 21421043

2011

Entrez Id: 2571
Gene Symbol: GAD1
GAD1
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.400 Biomarker CTD_human Schizophrenia subjects showed significant decreases in mRNA levels of GAD(67), GAD(65), GAT-1, mGluR2, and neuronal nitric oxide synthase. 18923069

2008

Entrez Id: 2572
Gene Symbol: GAD2
GAD2
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.380 Biomarker CTD_human Schizophrenia subjects showed significant decreases in mRNA levels of GAD(67), GAD(65), GAT-1, mGluR2, and neuronal nitric oxide synthase. 18923069

2008

Entrez Id: 6529
Gene Symbol: SLC6A1
SLC6A1
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.540 Biomarker CTD_human Schizophrenia subjects showed significant decreases in mRNA levels of GAD(67), GAD(65), GAT-1, mGluR2, and neuronal nitric oxide synthase. 18923069

2008

Entrez Id: 2912
Gene Symbol: GRM2
GRM2
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.400 Biomarker CTD_human Schizophrenia subjects showed significant decreases in mRNA levels of GAD(67), GAD(65), GAT-1, mGluR2, and neuronal nitric oxide synthase. 18923069

2008

Entrez Id: 1401
Gene Symbol: CRP
CRP
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.400 Biomarker PSYGENET Schizophrenia may be associated with inflammatory reactions and C-reactive protein (CRP) is a nonspecific serum protein marker for persisting inflammatory states. 19619902

2009

Entrez Id: 1020
Gene Symbol: CDK5
CDK5
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.310 Biomarker PSYGENET Schizophrenia is associated with dysregulation of a Cdk5 activator that regulates synaptic protein expression and cognition. 21772061

2011

Entrez Id: 885
Gene Symbol: CCK
CCK
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.400 Biomarker PSYGENET Cholecystokinin A receptors (CCKAR) modulate CCK-stimulated dopamine release, and mutations in the CCKAR gene may predispose affected individuals to schizophrenia. 11549403

2001

Entrez Id: 5173
Gene Symbol: PDYN
PDYN
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.330 Biomarker PSYGENET Prodynorphin and kappa opioid receptor mRNA expression in the cingulate and prefrontal cortices of subjects diagnosed with schizophrenia or affective disorders. 11576758

2001

Entrez Id: 2346
Gene Symbol: FOLH1
FOLH1
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.320 Biomarker PSYGENET Glutamate carboxypeptidase II gene expression in the human frontal and temporal lobe in schizophrenia. 14560319

2004

Entrez Id: 7148
Gene Symbol: TNXB
TNXB
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.430 Biomarker PSYGENET TNXB locus may be a candidate gene predisposing to schizophrenia. 14755442

2004

Entrez Id: 5173
Gene Symbol: PDYN
PDYN
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.330 Biomarker PSYGENET PDYN-946C>G polymorphism demonstrated an association with population susceptibility to schizophrenia. 15301734

2004

Entrez Id: 259217
Gene Symbol: HSPA12A
HSPA12A
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.310 Biomarker PSYGENET HSPA12A messenger ribonucleic acid was significantly reduced (p < .01; mean log2 optical density difference = -.84) across subjects with schizophrenia but not in the DLPFC of subjects with major depression or in monkeys chronically treated with haloperidol. 15601604

2004