×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
GeneticVariation
UNIPROT
Multiple colorectal adenomas, classic adenomatous polyposis, and germ-line mutations in MYH.
12606733
2003
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
GeneticVariation
CLINVAR
The thorough screening of the MUTYH gene in a large French cohort of sporadic colorectal cancers.
17931073
2007
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
GeneticVariation
CLINVAR
MUTYH-associated polyposis (MAP).
20663686
2011
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
GeneticVariation
CLINVAR
Loss of MUTYH function in human cells leads to accumulation of oxidative damage and genetic instability.
23108399
2013
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
GeneticVariation
UNIPROT
MUTYH-associated polyposis: 70 of 71 patients with biallelic mutations present with an attenuated or atypical phenotype.
16557584
2006
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
GeneticVariation
CLINVAR
First evidence for digenic inheritance in hereditary colorectal cancer by mutations in the base excision repair genes.
21195604
2011
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
GeneticVariation
CLINVAR
MUTYH mediates the toxicity of combined DNA 6-thioguanine and UVA radiation.
25638157
2015
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
GeneticVariation
CLINVAR
Similar colorectal cancer risk in patients with monoallelic and biallelic mutations in the MYH gene identified in a population with adenomatous polyposis.
17949294
2007
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
GeneticVariation
CLINVAR
Implication of adenomatous polyposis coli and MUTYH mutations in familial colorectal polyposis.
19279422
2009
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
GeneticVariation
CLINVAR
Germline mutations but not somatic changes at the MYH locus contribute to the pathogenesis of unselected colorectal cancers.
12707038
2003
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
GeneticVariation
CLINVAR
Prevalence of the Y165C, G382D and 1395delGGA germline mutations of the MYH gene in Italian patients with adenomatous polyposis coli and colorectal adenomas.
14999774
2004
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
GeneticVariation
UNIPROT
Heterogeneous molecular mechanisms underlie attenuated familial adenomatous polyposis.
18091433
2007
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
GeneticVariation
CLINVAR
Idiopathic gastric acid hypersecretion in a patient with MUTYH-associated polyposis.
19806110
2009
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
GeneticVariation
CLINVAR
Germline MUTYH (MYH) mutations in Portuguese individuals with multiple colorectal adenomas.
15366000
2004
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
GeneticVariation
CLINVAR
Distinct functional consequences of MUTYH variants associated with colorectal cancer: Damaged DNA affinity, glycosylase activity and interaction with PCNA and Hus1.
26377631
2015
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
GeneticVariation
CLINVAR
The potential for increased clinical sensitivity in genetic testing for polyposis colorectal cancer through the analysis of MYH mutations in North American patients.
15635083
2005
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
GeneticVariation
CLINVAR
Identification of a Variety of Mutations in Cancer Predisposition Genes in Patients With Suspected Lynch Syndrome.
25980754
2015
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
GeneticVariation
CLINVAR
Prevalence of MYH germline mutations in Swiss APC mutation-negative polyposis patients.
16287072
2006
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
GeneticVariation
CLINVAR
Contribution of APC and MUTYH mutations to familial adenomatous polyposis susceptibility in Hungary.
26446593
2016
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
GeneticVariation
CLINVAR
Risk of extracolonic cancers for people with biallelic and monoallelic mutations in MUTYH.
27194394
2016
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
GeneticVariation
CLINVAR
Multiple gene sequencing for risk assessment in patients with early-onset or familial breast cancer.
26824983
2016
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
GeneticVariation
CLINVAR
Genetic instability in lymphoblastoid cell lines expressing biallelic and monoallelic variants in the human MUTYH gene.
24569162
2014
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
GeneticVariation
CLINVAR
Immunohistochemical expression of MYH protein can be used to identify patients with MYH-associated polyposis.
16890597
2006
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
GeneticVariation
UNIPROT
Germline MUTYH (MYH) mutations in Portuguese individuals with multiple colorectal adenomas.
15366000
2004
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
GeneticVariation
CLINVAR
Comprehensive analysis of the contribution of germline MYH variation to early-onset colorectal cancer.
14991577
2004