Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
MICROVASCULAR COMPLICATIONS OF DIABETES, SUSCEPTIBILITY TO, 1(finding)
0.400 Biomarker CTD_human

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.400 Biomarker CTD_human VEGF promoter polymorphisms +405 and -460 were examined in 596 CHF patients enrolled in the Metoprolol CR/XL Randomized Intervention Trial in Heart Failure (MERIT-HF) study and in 187 healthy controls. 15880336

2005

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0035412
Disease: Rhabdomyosarcoma
Rhabdomyosarcoma
0.380 Biomarker CTD_human Vascular endothelial growth factor acts in an autocrine manner in rhabdomyosarcoma cell lines and can be inhibited with all-trans-retinoic acid. 16116481

2005

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
Depressive Disorder, Treatment-Resistant
0.320 Biomarker PSYGENET Vascular endothelial growth factor (VEGF) polymorphism is associated with treatment resistant depression. 20417690

2010

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.310 Biomarker PSYGENET Vascular endothelial growth factor (VEGF) is thought to be involved in the pathophysiology of mood disorders and the target of antidepressants. 21721043

2013

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0017636
Disease: Glioblastoma
Glioblastoma
0.400 Biomarker CTD_human A cDNA-microarray analysis of camptothecin resistance in glioblastoma cell lines. 16356833

2006

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme
0.400 Biomarker CTD_human A cDNA-microarray analysis of camptothecin resistance in glioblastoma cell lines. 16356833

2006

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0334588
Disease: Giant Cell Glioblastoma
Giant Cell Glioblastoma
0.300 Biomarker CTD_human A cDNA-microarray analysis of camptothecin resistance in glioblastoma cell lines. 16356833

2006

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.400 Biomarker CTD_human A novel tumor-promoting function residing in the 5' non-coding region of vascular endothelial growth factor mRNA. 18494554

2008

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0086692
Disease: Benign Neoplasm
Benign Neoplasm
0.340 Biomarker CTD_human A novel tumor-promoting function residing in the 5' non-coding region of vascular endothelial growth factor mRNA. 18494554

2008

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0242383
Disease: Age related macular degeneration
Age related macular degeneration
0.400 Biomarker CTD_human Aberrant retinal expression of vascular endothelial growth factor (VEGF) leading to neovascularization is a central feature of age-related macular degeneration and diabetic retinopathy, two leading causes of vision loss. 15788408

2005

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0011884
Disease: Diabetic Retinopathy
Diabetic Retinopathy
0.400 Biomarker CTD_human Aberrant retinal expression of vascular endothelial growth factor (VEGF) leading to neovascularization is a central feature of age-related macular degeneration and diabetic retinopathy, two leading causes of vision loss. 15788408

2005

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0004096
Disease: Asthma
Asthma
0.400 Biomarker CTD_human Acute and chronic changes of vascular endothelial growth factor (VEGF) in induced sputum of toluene diisocyanate (TDI)-induced asthma patients. 15201500

2004

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C2717961
Disease: Thrombotic Microangiopathies
Thrombotic Microangiopathies
0.400 Biomarker CTD_human Acute podocyte vascular endothelial growth factor (VEGF-A) knockdown disrupts alphaVbeta3 integrin signaling in the glomerulus. 22808199

2012

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0033687
Disease: Proteinuria
Proteinuria
0.300 Biomarker CTD_human Acute podocyte vascular endothelial growth factor (VEGF-A) knockdown disrupts alphaVbeta3 integrin signaling in the glomerulus. 22808199

2012

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C1565662
Disease: Acute Kidney Insufficiency
Acute Kidney Insufficiency
0.300 Therapeutic CTD_human Acute podocyte vascular endothelial growth factor (VEGF-A) knockdown disrupts alphaVbeta3 integrin signaling in the glomerulus. 22808199

2012

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C1565662
Disease: Acute Kidney Insufficiency
Acute Kidney Insufficiency
0.300 Biomarker CTD_human Acute podocyte vascular endothelial growth factor (VEGF-A) knockdown disrupts alphaVbeta3 integrin signaling in the glomerulus. 22808199

2012

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury
0.300 Biomarker CTD_human Acute podocyte vascular endothelial growth factor (VEGF-A) knockdown disrupts alphaVbeta3 integrin signaling in the glomerulus. 22808199

2012

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury
0.300 Therapeutic CTD_human Acute podocyte vascular endothelial growth factor (VEGF-A) knockdown disrupts alphaVbeta3 integrin signaling in the glomerulus. 22808199

2012

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0242350
Disease: Erectile dysfunction
Erectile dysfunction
0.340 Biomarker CTD_human Altered growth factor expression in the aging penis: the Brown-Norway rat model. 12002441

2002

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.400 Biomarker CTD_human Altered redox status accompanies progression to metastatic human bladder cancer. 18930813

2009

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0038220
Disease: Status Epilepticus
Status Epilepticus
0.340 Biomarker CTD_human Angiogenesis is associated with blood-brain barrier permeability in temporal lobe epilepsy. 17533168

2007

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0027686
Disease: Pathologic Neovascularization
Pathologic Neovascularization
0.320 Biomarker CTD_human Angiogenesis is associated with blood-brain barrier permeability in temporal lobe epilepsy. 17533168

2007

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0014556
Disease: Epilepsy, Temporal Lobe
Epilepsy, Temporal Lobe
0.300 Biomarker CTD_human Angiogenesis is associated with blood-brain barrier permeability in temporal lobe epilepsy. 17533168

2007

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0014558
Disease: Uncinate Epilepsy
Uncinate Epilepsy
0.300 Biomarker CTD_human Angiogenesis is associated with blood-brain barrier permeability in temporal lobe epilepsy. 17533168

2007