×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
0.900
GeneticVariation
CLINVAR
Immunosuppression. Binding by design.
1710317
1991
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
0.900
CausalMutation
CLINVAR
Genetic instability occurs in the majority of young patients with colorectal cancer.
7585065
1995
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
0.900
CausalMutation
CLINVAR
Seven new mutations in hMSH2, an HNPCC gene, identified by denaturing gradient-gel electrophoresis.
7726159
1995
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
0.900
CausalMutation
CLINVAR
Mutational analysis of the hMSH2 gene reveals a three base pair deletion in a family predisposed to colorectal cancer development.
7874129
1994
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
0.900
GeneticVariation
CLINVAR
Genetic instability in human ovarian cancer cell lines.
7937795
1994
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
0.900
CausalMutation
CLINVAR
hMSH2 mutations in hereditary nonpolyposis colorectal cancer kindreds.
8062247
1994
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
0.900
GeneticVariation
CLINVAR
hMSH2 mutations in hereditary nonpolyposis colorectal cancer kindreds.
8062247
1994
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
0.900
CausalMutation
CLINVAR
Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer.
8261515
1993
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
0.900
CausalMutation
CLINVAR
CpG dinucleotides in the hMSH2 and hMLH1 genes are hotspots for HNPCC mutations.
8566964
1996
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
0.900
CausalMutation
CLINVAR
Analysis of mismatch repair genes in hereditary non-polyposis colorectal cancer patients.
8574961
1996
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
0.900
CausalMutation
CLINVAR
Germ line mutations of hMSH2 and hMLH1 genes in Japanese families with hereditary nonpolyposis colorectal cancer (HNPCC): usefulness of DNA analysis for screening and diagnosis of HNPCC patients.
8581513
1995
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
0.900
CausalMutation
CLINVAR
Detection of new mutations in six out of 10 Swiss HNPCC families by genomic sequencing of the hMSH2 and hMLH1 genes.
8592341
1995
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
0.900
CausalMutation
CLINVAR
Genetic heterogeneity and unmapped genes for colorectal cancer.
8640829
1996
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
0.900
CausalMutation
CLINVAR
DNA mismatch repair gene mutations in 55 kindreds with verified or putative hereditary non-polyposis colorectal cancer.
8776590
1996
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
0.900
CausalMutation
CLINVAR
RNA-based mutation screening in hereditary nonpolyposis colorectal cancer.
8808596
1996
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
0.900
CausalMutation
CLINVAR
Microsatellite instability and mutation analysis of hMSH2 and hMLH1 in patients with sporadic, familial and hereditary colorectal cancer.
8872463
1996
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
0.900
CausalMutation
CLINVAR
Identification of a one-base germline deletion (codon 888 del C) and an intron splice acceptor site polymorphism in hMSH2.
9222765
1997
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
0.900
CausalMutation
CLINVAR
Hereditary nonpolyposis colorectal cancer families not complying with the Amsterdam criteria show extremely low frequency of mismatch-repair-gene mutations.
9311737
1997
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
0.900
CausalMutation
CLINVAR
MLH1 and MSH2 constitutional mutations in colorectal cancer families not meeting the standard criteria for hereditary nonpolyposis colorectal cancer.
9506527
1998
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
0.900
CausalMutation
CLINVAR
Systematic analysis of hMSH2 and hMLH1 in young colon cancer patients and controls.
9718327
1998
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
0.900
CausalMutation
CLINVAR
Interactions of human hMSH2 with hMSH3 and hMSH2 with hMSH6: examination of mutations found in hereditary nonpolyposis colorectal cancer.
9774676
1998
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
0.900
CausalMutation
CLINVAR
Microsatellite instability and mutation of DNA mismatch repair genes in gliomas.
9777949
1998
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
0.900
CausalMutation
CLINVAR
Reduction in hMSH2 mRNA levels by premature translation termination: implications for mutation screening in hereditary nonpolyposis colorectal cancer.
10080150
1999
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
0.900
CausalMutation
CLINVAR
Mismatch repair gene defects contribute to the genetic basis of double primary cancers of the colorectum and endometrium.
10196371
1999
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
0.900
CausalMutation
CLINVAR
Influence of selection criteria on mutation detection in patients with hereditary nonpolyposis colorectal cancer.
10375096
1999