×
Entrez Id:
8449
Gene Symbol:
DHX16
DHX16
Werner Syndrome
0.010
GeneticVariation
BEFREE
Werner's syndrome (WS), a representative progeroid syndrome with chromosomal instability caused by the mutation of RecQ type DNA/RNA helicase , manifests skin changes similar to those observed in systemic sclerosis (SSc).
11138345
2001
×
Entrez Id:
55308
Gene Symbol:
DDX19A
DDX19A
Werner Syndrome
0.010
GeneticVariation
BEFREE
Werner's syndrome (WS), a representative progeroid syndrome with chromosomal instability caused by the mutation of RecQ type DNA/RNA helicase , manifests skin changes similar to those observed in systemic sclerosis (SSc).
11138345
2001
×
Entrez Id:
9879
Gene Symbol:
DDX46
DDX46
Werner Syndrome
0.010
GeneticVariation
BEFREE
Werner's syndrome (WS), a representative progeroid syndrome with chromosomal instability caused by the mutation of RecQ type DNA/RNA helicase , manifests skin changes similar to those observed in systemic sclerosis (SSc).
11138345
2001
×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
Biomarker
BEFREE
WRN cell survival and the generation of viable mitotic recombinant progeny could be rescued by expressing wild-type WRN protein or by expressing the bacterial resolvase protein RusA.
12242278
2002
×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
GeneticVariation
BEFREE
Werner's syndrome (WS ) is a premature ageing disease caused by a mutation in the WRN gene.
16362795
2005
×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
GeneticVariation
BEFREE
Werner syndrome and mutations of the WRN and LMNA genes in France.
16786514
2006
×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
GeneticVariation
BEFREE
Werner syndrome (WS ) is a rare human premature aging disease caused by mutations in the gene encoding the RecQ helicase WRN .
17284601
2007
×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
Biomarker
BEFREE
Werner syndrome (WS ) is a premature aging and cancer-prone disease caused by loss of the RecQ helicase WRN protein.
17624410
2007
×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
GeneticVariation
BEFREE
Werner syndrome is an autosomal recessive disease of premature aging caused by a polymorphic C1367T mutation in the Werner (WRN ) gene.
20808731
2010
×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
GeneticVariation
BEFREE
Werner syndrome (WS ) is an autosomal recessive progeroid disorder caused by mutations in the WRN DNA helicase.
22188495
2012
×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
Biomarker
BEFREE
Werner syndrome (WS ) is a disorder characterized by features of premature aging and increased cancer that is caused by loss of the RecQ helicase WRN .
22871734
2012
×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
GeneticVariation
BEFREE
Werner syndrome is caused by mutations in the DNA repair Werner helicase (WRN ) gene and characterized by accelerated aging including cataracts.
23334603
2013
×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
GeneticVariation
BEFREE
Werner syndrome (WS) is a rare autosomal recessive disorder caused by mutations in the WRN gene.
23583337
2013
×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
GeneticVariation
BEFREE
Werner syndrome is genetically linked to mutations in WRN that encodes a DNA helicase-nuclease believed to operate at stalled replication forks.
23867477
2013
×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
GeneticVariation
BEFREE
Werner syndrome (WS ) is a premature aging disorder caused by WRN protein deficiency.
25931448
2015
×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
GeneticVariation
BEFREE
Werner syndrome (i.e., adult progeria) is a rare autosomal recessive disorder caused by mutations of the WRN gene, which is characterized by the premature appearance of features associated with normal aging and cancer predisposition.
27931782
2017
×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
GeneticVariation
BEFREE
Werner syndrome (WS ) is a progeroid-like syndrome caused by WRN gene mutations.
28158503
2017
×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
GeneticVariation
BEFREE
Werner syndrome (WS ) is a rare inheritable progeroid syndrome caused by a mutation in the WRN gene.
28738022
2017
×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
GeneticVariation
BEFREE
Werner syndrome (WRN ) gene variants and their association with altered function and age-associated diseases.
29146545
2018
×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
GeneticVariation
BEFREE
Werner syndrome is a rare autosomal recessive disorder where Werner (WRN ) gene is mutated.
31085421
2019
×
Entrez Id:
83990
Gene Symbol:
BRIP1
BRIP1
Werner Syndrome
0.010
Biomarker
BEFREE
Werner syndrome protein (WRN) and Fanconi anemia group J protein (FANCJ ) are human DNA helicases that contribute to genome maintenance.
31570747
2019
×
Entrez Id:
164045
Gene Symbol:
HFM1
HFM1
Werner Syndrome
0.100
GeneticVariation
BEFREE
WRN helicase gene strongly suggests that most of the chromosomes carrying either mutation 1 or 4 were derived from two single founders.
9048918
1997
×
Entrez Id:
54932
Gene Symbol:
EXD3
EXD3
Werner Syndrome
0.010
Biomarker
BEFREE
Mut-7 of C. elegans, required for transposon silencing and RNA interference, is a homolog of Werner syndrome helicase and RNaseD.
10535732
1999
×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
GeneticVariation
BEFREE
WRN is encoded by the gene that when mutated causes Werner's syndrome .
10540192
1999
×
Entrez Id:
641
Gene Symbol:
BLM
BLM
Werner Syndrome
0.100
Biomarker
BEFREE
BLM is found primarily in nuclear domain 10 except during S phase when it colocalizes with the Werner syndrome gene product, WRN, in the nucleolus.
10779560
2000