Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3240
Gene Symbol: HP
HP
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.360 GeneticVariation BEFREE Preliminary data suggest the possibility of linkage between the alpha-haptoglobin locus and third component of complement locus and depression spectrum disease, a depression which is familially defined by the presence of alcoholism in the first-degree family member. 401356

1979

Entrez Id: 3240
Gene Symbol: HP
HP
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.360 Biomarker BEFREE The results show virtually no evidence of linkage between depression spectrum disease and C3, but suggestive evidence (lod score = 1.03) of linkage between depression spectrum disease and alpha-haptoglobin (both these linkages were previously suggested by significant results in sib-pair analyses). 431798

1979

Entrez Id: 100379198
Gene Symbol: ECT
ECT
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.100 Biomarker BEFREE The presence of a family history of depression may be predictive to some extent of a good response to adequate tricyclic medication or ECT. 453352

1979

Entrez Id: 6046
Gene Symbol: BRD2
BRD2
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.020 Biomarker BEFREE Save for a depression in plasma FSH in the early follicular phase, this hormone, as wells as LH and progesterone patterns in our patient, were similar to the comparison cohorts. 498052

1979

Entrez Id: 3240
Gene Symbol: HP
HP
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.360 Biomarker BEFREE Preliminary data indicate that depression spectrum disease may be linked to such genetic markers as C3 or alpha-haptoglobin. 760696

1979

Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.320 Biomarker PSYGENET Interictal behavioral disturbances: a search for molecular substrates. 1337448

1992

Entrez Id: 847
Gene Symbol: CAT
CAT
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.100 AlteredExpression BEFREE Depression of catalase gene expression in the liver of tumor bearing nude mice. 1472018

1992

Entrez Id: 1392
Gene Symbol: CRH
CRH
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.600 Biomarker BEFREE CRF overproduction has been implicated in affective disorders, such as depression and anorexia nervosa, and may lead to Cushing's syndrome. 1597149

1992

Entrez Id: 10882
Gene Symbol: C1QL1
C1QL1
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.040 Biomarker BEFREE CRF overproduction has been implicated in affective disorders, such as depression and anorexia nervosa, and may lead to Cushing's syndrome. 1597149

1992

Entrez Id: 3688
Gene Symbol: ITGB1
ITGB1
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.010 Biomarker BEFREE CIAA+ICA+ first-degree relatives of individuals with type I diabetes have increased numbers of CD4 cells bearing the CD45R antigen and reciprocal depressions of the CD4 cells bearing the CD29 determinant. 1827080

1991

Entrez Id: 5788
Gene Symbol: PTPRC
PTPRC
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.010 Biomarker BEFREE CIAA+ICA+ first-degree relatives of individuals with type I diabetes have increased numbers of CD4 cells bearing the CD45R antigen and reciprocal depressions of the CD4 cells bearing the CD29 determinant. 1827080

1991

Entrez Id: 2152
Gene Symbol: F3
F3
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.010 AlteredExpression BEFREE There was a significant depression (66%) of the induced level of TF mRNA expression in response to lipopolysaccharide. 2293902

1990

Entrez Id: 353
Gene Symbol: APRT
APRT
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.330 Biomarker PSYGENET Similar studies with somatic cell mutants deficient in some component of cyclic AMP action or metabolism indicated that the depression in purine synthetic rates required G1 arrest and did not result from cell death. 2414305

1985

Entrez Id: 2
Gene Symbol: A2M
A2M
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.300 Biomarker PSYGENET CF heterozygotes shared the decrease of alpha 1-lipoprotein with the patients while exhibiting small but significant depressions of alpha 2-macroglobulin and IgG. 2432615

1987

Entrez Id: 28954
Gene Symbol: REM1
REM1
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.100 Biomarker BEFREE Siblings with non-reduced REM latency had a higher rate of depression (36.8%) than non-reduced REM latency parents (0.0%). 2521654

1989

Entrez Id: 7200
Gene Symbol: TRH
TRH
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.340 Biomarker BEFREE The results of the TRH test and the DST point to similar endocrinological patterns in alcoholics as in depressive patients and thus support the hypothesis of a link between alcoholism and depression. 2543997

1989

Entrez Id: 7200
Gene Symbol: TRH
TRH
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.340 Biomarker PSYGENET The results of the TRH test and the DST point to similar endocrinological patterns in alcoholics as in depressive patients and thus support the hypothesis of a link between alcoholism and depression. 2543997

1989

Entrez Id: 667
Gene Symbol: DST
DST
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.050 Biomarker BEFREE The results of the TRH test and the DST point to similar endocrinological patterns in alcoholics as in depressive patients and thus support the hypothesis of a link between alcoholism and depression. 2543997

1989

Entrez Id: 3855
Gene Symbol: KRT7
KRT7
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.100 GeneticVariation BEFREE Forty-three subjects (77%) evidenced mild depression of which 13 (23%) reported moderate-severe symptoms by the Beck Depression Inventory--a finding confirmed with Hamilton Rating Scale for Depression and the SCL-90-D scale. 2934456

1985

Entrez Id: 6886
Gene Symbol: TAL1
TAL1
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.100 GeneticVariation BEFREE Forty-three subjects (77%) evidenced mild depression of which 13 (23%) reported moderate-severe symptoms by the Beck Depression Inventory--a finding confirmed with Hamilton Rating Scale for Depression and the SCL-90-D scale. 2934456

1985

Entrez Id: 51540
Gene Symbol: SCLY
SCLY
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.100 GeneticVariation BEFREE Forty-three subjects (77%) evidenced mild depression of which 13 (23%) reported moderate-severe symptoms by the Beck Depression Inventory--a finding confirmed with Hamilton Rating Scale for Depression and the SCL-90-D scale. 2934456

1985

Entrez Id: 2996
Gene Symbol: GYPE
GYPE
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.310 Biomarker BEFREE Indications of linkage between familial pure depressive disease and MNS and depression spectrum disease and ORM were found, as had been previously suggested. 3233232

1988

Entrez Id: 2996
Gene Symbol: GYPE
GYPE
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.310 Biomarker PSYGENET Indications of linkage between familial pure depressive disease and MNS and depression spectrum disease and ORM were found, as had been previously suggested. 3233232

1988

Entrez Id: 2993
Gene Symbol: GYPA
GYPA
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.020 Biomarker BEFREE Indications of linkage between familial pure depressive disease and MNS and depression spectrum disease and ORM were found, as had been previously suggested. 3233232

1988

Entrez Id: 2316
Gene Symbol: FLNA
FLNA
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.020 Biomarker BEFREE Indications of linkage between familial pure depressive disease and MNS and depression spectrum disease and ORM were found, as had been previously suggested. 3233232

1988